Wolves manager Mick McCarthy will make a late fitness check on striker Steven Fletcher.
Three-goal leading scorer Fletcher has missed the last three games with a calf problem but returned to full training on Friday.
McCarthy expects playmaker Jamie O'Hara (knee) and Stephen Hunt (back) to be fit after missing training during the early part of the week following the 3-1 reversal at Manchester City.
Wigan manager Roberto Martinez is sweating on the fitness of Mohamed Diame.
Scans have shown Diame suffered no major damage to his ankle following a tough challenge from Fulham's Steve Sidwell last week, but the Senegal midfielder will not train until Saturday and will only be involved if he suffers no reaction.
Latics will be without skipper Gary Caldwell, who serves a one-match suspension after picking up five bookings this season.
Wolves (from): Hennessey, De Vries, Stearman, Johnson, Berra, Ward, Hammill, Henry, O'Hara, Jarvis, Hunt, Doyle, Doherty, Elokobi, Craddock, Milijas, Guedioura, Edwards, Ebanks-Blake, Fletcher, Vokes.
Wigan (from): Al Habsi, Boyce, Alcaraz, Figueroa, Watson, Diame, Moses, Gomez, McCarthy, Di Santo, Jones, Pollitt, Stam, Van Aanholt, McArthur, Lopez, Thomas, Sammon, Maloney, Crusat, Gohouri, Rodallega, McCarthy.