Rangers will be without Lee Wallace after he was ruled out for a couple of weeks with a hamstring strain.
Steven Naismith returns from suspension after sitting out the Europa League match against Maribor, while Steven Whittaker - who was also banned for the European clash - has a chance of making his return following a broken toe and Jordan McMillan is expected to shake off a calf strain.
New signing Alejandro Bedoya is set to be added to the squad for the first time but Kyle Bartley has returned to Arsenal to have a groin injury assessed and David Weir (hamstring), Sasa Papac (illness) and Lee McCulloch (knee) are likely to remain on the sidelines.
Aberdeen are hopeful Chris Clark and Kari Arnason will recover from the injuries that forced them off against Dundee in midweek in time for the clash with Rangers.
Rob Milsom will return from a groin problem while Yoann Folly is back in the squad after recovering from a broken leg.
Jamie Langfield is the only player on the sidelines but he is close to returning following his brain seizure.
Rangers (from): McGregor, Goian, McMillan, Perry, Ortiz, Davis, Naismith, Wylde, Kerkar, Lafferty, Fleck, Jelavic, Bocanegra, Bedoya, Whittaker, Healy, Hutton, Alexander.
Aberdeen (from): Jason Brown, Foster, Considine, Arnason, Mawene, Magennis, Paton, Milsom, Osbourne, Pawlett, Megginson, Vernon, Chalali, Mackie, McArdle, Clark, Fyvie, Folly, Jack.