Sam Allardyce will ring the changes for the Hammers.
The West Ham boss will give a number of fringe players a chance, meaning goalkeeper Ruud Boffin, defender Abdoulaye Faye, midfielders Pablo Barrera, Julien Faubert and Junior Stanislas as well as striker Freddie Sears should be involved.
Allardyce could also hand a full debut to new forward John Carew, who got 20 minutes as a substitute in the 2-2 draw with Leeds on Sunday.
Left-back George McCartney may also be added to the squad for the first time since he rejoined the club from Sunderland if he is fit enough.
Defender Jordan Brown and winger Gary O'Neil are still on the sidelines with ankle injuries.
Goalkeeper Ross Worner and midfielder Jermaine McGlashan are pushing for first-team selection for Aldershot.
Manager Dean Holdsworth has no injury concerns ahead of the game but may choose to make a couple of tactical changes following a 2-0 defeat against Morecambe at the weekend.
Holdsworth will name his strongest team possible in the hope of causing an upset against the Hammers, but may choose to select Worner ahead of Jamie Young in goal.
McGlashan is less likely to make an immediate return to the starting 11 and may have to be satisfied with a place on the bench.