Wycombe manager Gary Waddock will make changes ahead of the game.
Waddock perhaps feels he needs to freshen up his side after allowing Bury "too much room" during the 2-0 defeat to the Shakers on Saturday.
The likes of Leon Johnson, Marvin McCoy, Ben Harding and Kadeem Harris, who all started the first-round tie against Colchester, will come into contention along with Scott Rendell, Matt Bloomfield and Elliot Benyon.
Midfielder Stuart Lewis could be on the bench having ben ruled out so far this season with a virus.
Winger Kevin Betsy is also available following his return from the Seychelles where he helped his country to win the Indian Ocean Games.
Forest manager Steve McClaren is expected to make changes for the clash.
Strikers Ishmael Miller and Robbie Findley and midfielder Radoslaw Majewski were substitutes against Leicester on Saturday but their introduction helped change the game as Forest fought back from 2-0 down to earn a draw at the City Ground.
The trio might have played their way into McClaren's plans for the second round tie, while defender Joel Lynch could also come into contention.
Forwards Joe Garner and Marcus Tudgay were left out of the squad at the weekend and will hope to be involved in Buckinghamshire. However, midfielders Paul Anderson (groin) and Guy Moussi (calf) are still trying to regain fitness.
Experienced midfielder George Boateng, who scored the injury-time equaliser against Leicester, was rested against Notts County in the first round and may well take a back seat once again.