Bryan Ruiz is set for a return to the Fulham squad.
The 26-year-old deadline day signing was ineligible for the midweek Europa League clash with FC Twente, whom he played for in the Champions League play-offs earlier in the season.
Aaron Hughes also missed the Group K tie with a knee injury and is a doubt, while Dickson Etuhu is struggling with a thigh injury.
Manchester City midfielder James Milner has been ruled out.
Milner missed the midweek Champions League game against Napoli after a clash of heads in last week's defeat of Wigan.
Midfielder Nigel de Jong (foot) remains 10 days to two weeks away from fitness while full-back Aleksandar Kolarov is not hindered by a broken nose.
Fulham (from): Schwarzer, Etheridge, Baird, Hangeland, Hughes, Kelly, Grygera, JA Riise, BH Riise, Duff, Sidwell, Dembele, Dempsey, Etuhu, Gecov, Murphy, Sa, Zamora, Johnson.
Manchester City (from): Hart, Zabaleta, Kompany, Lescott, Kolarov, Richards, Clichy, K Toure, Savic, Nasri, Barry, Y Toure, Silva, Johnson, Dzeko, Balotelli, Tevez, Aguero, Razak, Pantilimon.