Marlon Harewood could make his first Nottingham Forest appearance in more than eight years.
Harewood, who began his career with the Reds, has rejoined the club on a deal until the end of the season following a spell in Chinese football.
Forest failed to get international clearance for the striker to play in the Championship game at Ipswich on Bank Holiday Monday but hope to have the paperwork completed in time for the weekend.
Harewood's last appearance for the club was a goalscoring one in a 2-2 draw at Wigan in the old Division One on November 22, 2003. A couple of days later he signed for West Ham in a £500,000 deal.
Defender Joel Lynch returns from suspension and midfielder Paul Anderson (hamstring) and striker Dexter Blackstock (calf) could also be available again after injury lay-offs. Striker Robbie Findley remains a doubt with a shoulder problem.
Leicester are monitoring full-backs Paul Konchesky and Lee Peltier.
Both players sustained injuries during the 1-1 home draw against Portsmouth on New Year's Eve and missed the victory at Crystal Palace on Bank Holiday Monday as Tom Kennedy and Academy product Liam Moore stepped in.
"We will have a look at their situations," said City boss Nigel Pearson. "Konchesky has a dead leg and Peltier had a bit of a hamstring and groin tightness, and they weren't close enough to make it for the Palace game."
With Moore cup-tied after playing in the competition during a loan spell at Bradford and John Pantsil set to link up with the Ghana squad on Friday ahead of the African Nations Cup, Pearson will hope both players win their fitness battle.
Leicester are waiting to hear whether Ivory Coast centre-half Sol Bamba can play before he too jets off for the African Nations Cup. However, Pearson will definitely be without Steve Howard after the burly striker was sent off against Palace and he begins a two-match suspension.
The tie on Saturday will be only the second time the East Midlands rivals have met in FA Cup. The only previous meeting in the competition came 110 years ago, in February 1901 at the City Ground, and Forest were 5-1 winners.