On-loan Manchester United midfielder Danny Drinkwater is set to return to action for Barnsley.
The 21-year-old has rejoined the Tykes on loan until the end of the season after his original four-month loan came to an end earlier this week.
Drinkwater had missed the last four matches with a thigh injury but is set to come back into contention to face the Premier League side.
The return of Drinkwater has boosted the Barnsley midfield following the news that skipper Jacob Butterfield will be out for the rest of the season after suffering an anterior cruciate ligament injury in the New Year's Eve win over Leeds.
Fellow midfielder Jim O'Brien remains on the sidelines with a stomach muscle problem.
New Swansea signing Gylfi Sigurdsson is in line to make his debut.
The Iceland international joined on loan from Hoffenheim earlier this week and could be handed an immediate chance to impress with manager Brendan Rodgers set to make changes following the victory at Aston Villa.
Goalkeeper Gerhard Tremmel could also be handed a debut, four months after joining the club, with Michel Vorm set for a rest after excelling so far this term.
Swansea (from): Vorm, Williams, Taylor, Caulker, Britton, Orlandi, Graham, Sinclair, Dyer, Dobbie, Routledge, Monk, Lita, Moore, Bessone, Rangel, Allen, Tremmel, Agustien, Gower, Richards, Alfei, Sigurdsson.