Shaun Batt will be added to the Crawley squad.
Batt has joined the Red Devils on a month's loan from Millwall and could be set for an immediate debut.
Fellow strikers Karl Hawley and Billy Clarke are also available after they were cup-tied against Stoke on Sunday.
But right-back David Hunt is set to miss out with the foot injury he suffered in a challenge with Rory Delap which saw the Potters midfielder sent off.
Scott Neilson came on for Hunt and is likely to start against the Shrimps.
First-choice goalkeeper Scott Shearer needs a knee operation so Watford loanee Rene Gilmartin, who started Sunday's 2-0 defeat, will make his league debut.
Morecambe defender Will Haining is an injury doubt for the re-arranged trip.
Haining was replaced at half-time during the weekend draw at AFC Wimbledon and could miss out against the Red Devils due to a tight hamstring.
Andy Parrish stepped in for Haining against the Dons and is in line for a first start following an absence of his own with illness in recent weeks.
Shrimps boss Jim Bentley is boosted by the presence of winger Izak Reid in his squad for the first time this calendar year.
Reid has endured a lengthy spell on the sidelines with a hernia problem but is now back in full training.
Centre-back Paul Scott remains a long-term absentee with a serious knee injury.
