Leading scorer Chris Beardsley is an injury concern for Stevenage.
Beardsley was forced off midway through the first half of the defeat to League One leaders Charlton on Saturday with a hamstring problem.
The nine-goal striker is being assessed by the club's medical staff but is a doubt.
Jon Ashton also went off at The Valley after complaining of blurred vision following a clash of heads with Boro skipper Mark Roberts. However, the defender should be fit to face the Terriers on Tuesday night.
Stevenage have dropped out of the play-off places after back-to-back defeats and manager Gary Smith knows the visit of fourth-placed Huddersfield has now taken on more significance.
He said: "The disappointment now is we've lost two games on the spin but we'll look towards Tuesday's game which is an important fixture for us given that Carlisle won late on against Yeovil on Saturday."
Meanwhile, Huddersfield will be without leading goalscorer Jordan Rhodes as Simon Grayson takes charge of his second game since replacing Lee Clark as manager.
Rhodes, who scored his 30th goal of the season in Saturday's 2-0 win over Exeter, is on international duty with Scotland Under-21s, but could be doubtful after suffering a dead-leg at the weekend.
Alan Lee partnered Rhodes in Grayson's first game in charge against Exeter, with Lee Novak stepping off the substitutes' bench, but Kallum Higginbotham, a recent signing from Falkirk, provides another option and Danny Cadamarteri can also play in a central attacking role.
Grayson has no new injury or suspension worries, but skipper Peter Clarke and midfielder Tommy Miller both remain sidelined after respective double hernia operations.
Town are currently fourth in the table, four points behind second-placed Sheffield United.