Jim Bentley will assess striker Richard Brodie before Morecambe look to continue their impressive start to the season.
On-loan Crawley man Brodie started Saturday's 3-0 opening league win over Exeter having started on the bench due to a calf problem when the Shrimps shocked Blackpool in the Capital One Cup.
Brodie made way for Danny Carlton before the hour at St James' Park but remains in contention to start against his former club.
Experienced defender Nick Fenton was also sidelined with a calf complaint during pre-season and has been an unused substitute for the first two games of the campaign with Chris McCready impressing at centre-back.
Midfielder Andy Fleming is on a rich vein of form having followed up his winning goal at Blackpool with a first-half brace on Saturday.
York manager Gary Mills could be tempted to make changes after his side marked their return to the Football League on Saturday with a defeat to Wycombe.
The Minstermen, back in the league following an eight-year absence, have no new injury or suspension problems, but Mills felt his side leaked goals in the 3-1 home defeat to Wycombe far too easily.
Defender Lanre Oyebanjo was restricted to a place on the substitutes' bench due to a thigh injury, but could return to stiffen up the back four, while striker Jamie Reed is hoping to shake off the hamstring strain that kept him out at the weekend.
Midfield trio Jon Challinor, Matty Blair and John McReady all staked their claims for a place in Mills' starting line-up following their introduction in the second half against Wycombe.
Summer signings Lee Bullock, Jonathan Smith and Michael Coulson all made their league debuts and are expected to retain their places in the side.