Chico Flores and Wayne Routledge are expected to be fit to face the Black Cats as Swansea look to continue their 100% start to the Premier League season.
Defender Flores (groin) and winger Routledge (thigh) have had niggling injuries but manager Michael Laudrup is confident they will be fit to face the Black Cats.
New signing Ki Sung yueng could be set for his Premier League bow after making his debut against Barnsley in midweek.
Swansea are set to complete the signing of Valencia winger Pablo Hernandez, but he will not be included in the squad.
Adam Johnson and Steven Fletcher could both be handed league debuts for Sunderland.
The pair, who signed for the Black Cats a week ago on Friday, started Tuesday night's Capital One Cup second round victory over Morecambe and will hope to retain their places for the game at the Liberty Stadium.
Phil Bardsley (ankle), Wes Brown (knee) and David Vaughan (ankle) remain on the sidelines, while Ahmed Elmohamady has joined Hull on loan.
Swansea (from): Vorm, Taylor, Flores, Tate, Williams, Britton, Michu, Graham, Dyer, Routledge, Monk, Shechter, Lita, Moore, De Guzman, Rangel, Ki, Tremmel, Agustien, Gower, Richards, Bartley, Davies.
Sunderland (from): Westwood, Mignolet, Cuellar, O'Shea, Bramble, Kilgallon, Cattermole, Larsson, Gardner, Colback, McClean, Johnson, Sessegnon, Meyler, Campbell, Saha, Fletcher, Wickham, Ji.