The final whistle goes and Everton have run out deserved 3-1 winners after inflicting the damage on Southampton during a 15-minute blitz in the first half. The Toffees remain very much among the leading pack in the Premier League, while Southampton appear to be facing a tough season after going down to a fifth defeat in six league games.
Leon Osman acknowledges the applause from the crowd as David Moyes shores things up further by bringing on Sylvain Distin.
Three minutes of stoppage time have been signalled, as Everton look to take the sting out of the game by passing it around in midfield.
Nigel Adkins gives it one last throw of the dice as Adam Lallana goes off to be replaced by Richard Chaplow for the closing stages.
Leon Osman hurts himself after sliding in for a challenge on James Ward-Prowse which was badly mistimed. Luckily the Southmapton player is okay, while Osman is also fine to continue.
Leighton Baines tries to swing in a cross but gets it all wrong and it nearly turns into a fantastic shot, but Paulo Gazzaniga stays alert to turn the ball over his bar and concede a corner.
A goal now would make things really interesting and Rickie Lambert comes close for Southampton as he aims a header at goal which forces Tim Howard to move to his right quickly and parry the ball away.
There is a growing sense of desperation about Southampton's attempts at goal as the clock ticks down, with Gaston Ramirez blazing over from 25 yards.
Nigel Adkins responds with a double change of his own, bringing on Emmanuel Mayuka and Ben Reeves for Nathaniel Clyne and Jay Rodriguez.
Kevin Mirallas has made a tremendous impact since his summer arrival and gets a deserved round of applause as he makes way for another new boy, Bryan Oviedo.
Marouane Fellaini can look unplayable at times and he has been in the mood ago this afternoon, showing great feet as well as his usual brawn.
Nikica Jelavic will not be getting his hands on the match ball this afternoon as he is replaced by Victor Anichebe for the final quarter of an hour.
Steven Pienaar has a chance to play in Marouane Fellaini but his pass is just too short and, although the midfielder wriggles free of his first defender, he cannot get past the second.
Having stemmed the tide, Southampton are now starting to press hard in an attempt to get back into this game and the crowd have gone quiet.
Gaston Ramirez makes a great run to latch on to Rickie Lambert's pass and dinks a delightful shot over Tim Howard from close range, only to see the ball drift narrowly wide of the far past.
Gaston Ramirez decides to go for goal from 25 yards and it is an ambitious effort which Tim Howards gets safely in behind and saves with ease.
Paulo Gazzaniga has had a busy shift this afternoon and he pulls of another smart save here, getting down to his right quickly to push away Kevin Mirallas' 20-yard strike.
Southampton dwell too long on the ball in an advanced area and by the time Frazer Richardson finally delivers a right-wing cross the strikers in the centre are static.
Gaston Ramirez tries to nod the ball on to Rickie Lambert but Tim Howard quickly rushes off his line and gets good distance on his punch.
Jay Rodriguez lets fly with a cross-cum-shot from wide on the right which flashes across goal.
Seamus Coleman's cross is too deep for Nikica Jelavic to have a go at goal but the striker does brilliantly to bring the ball under control and lay it off to Leon Osman, who bends an effort just wide from the edge of the area.
John Heitinga gets a shot away from the corner which takes a deflection and trickles agonisingly wide of Paulo Gazzaniga's right-hand post.
Marouane Fellaini stumbles out of a challenge from James Ward-Prowse before drilling a ferocious shot from distance which sends Paulo Gazzaniga scrambling to his right to make a fine save.
The second half has been more of an even contest so far and Southampton are getting on the ball quite a bit, but Everton look organised at the back and have a two-goal cushion.
The flag goes up for offside as Nikica Jelavic tries to run on to a long ball from the back, but the striker appreciates what was intended and raises his hand in acknowledgment.
Everton earn a corner and Leon Osman and Leighton Baines combine in a well-worked routine, before running the ball out of play.
Jay Rodriguez shoots first time after being picked out by Rickie Lambert 20 yards from goal, but his effort lacks power and Tim Howard makes a comfortable save.
Nigel Adkins resisted the temptation to make a change at half-time but he must be considering shuffling his pack if there is no change to the pattern of the game soon.
Everton look a bit more patient at the start of the second half, content just to pass it around in midfield rather than go for the jugular all the time.
Everton get the second half started and if they pick up where they left off at the end of the first period their fans are in for a real treat. Southampton will have other ideas, of course, and will feel they can still get back into this game.
The Everton fans stand to applaud as the half-time whistle goes, with David Moyes' men finding their form in wonderful style after a slow 15 minutes to take full control. It is 3-1 at the interval and if the Toffees keep going like that they could score a hatful, while Nigel Adkins will be mightily relieved to get the chance to regroup.
Leon Osman lets fly with a thumping half-volley which is deflected wide from a corner, and Marouane Fellaini then rattles the crossbar with a header.
Seamus Coleman brings out his box of tricks with a couple of delightful pieces of skill, which do not really get Everton anywhere but delight the fans.
Marouane Fellaini tries his luck from a tight angle inside the area but his effort is partially blocked and there is not much pace on the ball by the time Paulo Gazzaniga makes a routine save.
Everton are not taking their foot off the pedal at all at the moment and they have enjoyed a tremendous 15-minute spell. Can they add to their lead further before half-time?
Kevin Miralls picks out Nikica Jelavic with a cross to the back post but the striker tries to head the ball back for Marouane Fellaini this time and does not get it quite right.
GOAL Seamus Coleman does brilliantly to beat his man on the right wing and burst into the area, before delivering a floated cross to Nikica Jelavic at the back post. Paulo Gazzaniga gets a hand to the Croatian's powerful header but on this occasion cannot keep the ball out of his net.
Paulo Gazzaniga pulls off a wonderful acrobatic save to deny Nikica Jelavic as Everton hunt for a third goal.
Everton are suddenly all over Southampton and Nikica Jelavic's movement is causing all sorts of problems for the Saints defence.
GOAL! Everton turn the game in their favour as Nikica Jelavic provides the cutting edge to a flowing move by racing through the centre to latch on to Kevin Mirallas' excellent pass and slot his finish coolly past Paulo Gazzaniga.
Kevin Mirallas has been lively in the last few minutes and he switches flanks temporarily to try his luck on the left, only to be flagged offside as he picks up possession.
Referee Lee Probert calls for calm as Nathaniel Clyne brings down Kevin Mirallas in midfield to concede a free-kick and halt a threatening Everton counter-attack.
Leon Osman's equaliser has really lifted Everton and Nikica Jelavic does well to deliver a low cross between goalkeeper and defensive line, but unfortunately none of his team-mates have found their way into the centre.
GOAL! Southampton fail to clear a Kevin Mirallas cross and the ball breaks kindly for Leon Osman to smash a shot into the roof of the net from 10 yards and draw Everton level.
When Everton do get possession they look quite decent in the middle third, but then cannot find the killer pass and that is allowing Southampton to break with speed.
Phil Jagielka clears it behind for a corner with an unconvincing header as Everton are pegged back inside their own half.
Nikica Jelavic loses his footing just outside the area and falls down rather ungracefully, allowing Southampton's defenders to deal with a potentially dangerous attack.
Everton have not yet found their usual fluency and manager David Moyes will be furious with their performance in the opening quarter of an hour or so.
Southampton look really dangerous as Jay Rodriguez comes within inches of getting on the end of a Gaston Ramirez cross.
There are appeals for a penalty, from the crowd at least, as Nikica Jelavic goes down in the area under pressure from Frazer Richardson, but referee Lee Probert waves play on and replays show it was an excellent tackle.
It has been a very open start to the game at Goodison Park and now it is Leon Osman who has a chance to get on the score sheet with a header, but he cannot quite keep it down after having to jump high.
It should be two for Southampton as Jay Rodriguez shows a clean pair of heels to John Heitinga to give himself a clear run at goal, but Everton breathe a sigh of relief as he pokes his shot wide.
Marouane Fellaini shows his aerial prowess to flick on a header and win Everton a corner, which results in John Heitinga directing a free header straight at Paulo Gazzaniga.
GOAL! That is far too easy for Southampton and a first Premier League goal for Gaston Ramirez, with the club-record signing heading home unmarked from close range following abysmal defending at a corner. Goalkeeper Tim Howard was in no man's land as Adam Lallana delivered the set-piece.
Southampton gain a foothold in the game with a spell of possession and Maya Yoshida shows that he is a ball-playing defender as he looks to get involved in an attack, before being dispossessed by Seamus Coleman.
This time it is Seamus Coleman's turn to spring down the wing and deliver a cross, but it is not quite so accurate and drifts harmlessly out of play.
Leighton Baines drives forward on a typically powerful run and sends over a menacing cross, which Maya Yoshida does well to clear as Nikica Jelavic lurks behind.
It is a scrappy start from both sides as they trade long passes, with the ball barely making contact with the floor during the opening minute.
Southampton kick us off on a sunny afternoon at Goodison Park, and let us hope for a thrilling encounter with both sides playing good football.
Joe Murphy says: "Can only see one result today here in Sth Iran. That's a big win for Everton."
If results had gone their way today Everton could have moved to the top of the table, but that is no longer possible following the result of the early game between Arsenal and Chelsea at Emirates Stadium.
"Oliver and Joel, the Everton supporters from London, think that following their loss to Leeds United in the Capital One Cup, Everton and Moyes will be looking to get a win against Southampton. 4-0 to the Blues. Goals from Mirallas (2), Fellaini and Anichebe." Always good to get a feedback that's a joint effort.
Gabriel has been in touch, saying: "Southampton will be buoyed by their much needed win over Villa last week so I'd expect them to make it difficult for Everton and with a player of Rickie Lambert's doggedness leading the line and flair players around him they look like a team capable of scoring goals. Everton have always been a hardworking team though and I can't see that changing in this game. Think they will have the edge in what could be a good match. 3-2 to the Toffees."
Everton: Howard, Coleman, Heitinga, Jagielka, Baines, Mirallas, Neville, Osman, Pienaar, Fellaini, Jelavic. Subs: Mucha, Oviedo, Distin, Gueye, Vellios, Anichebe, Duffy.
Southampton: Gazzaniga, Richardson, Fonte, Yoshida, Clyne, Ramirez, Steven Davis, Ward-Prowse, Lallana, Lambert, Rodriguez. Subs: Kelvin Davis, Hooiveld, Do Prado, Mayuka, Chaplow, Reeves, Puncheon.
"This is Stewart MacLaren from a warm & windy Torrevieja in Spain saying that Everton will beat Southampton 3-1 at Goodison Park this afternoon with good goals from Leighton Baines, Fellaini & Nikica Jelavic."
Let me know your views and predictions by getting in touch at Lewis.Rutledge@bskyb.com, or via Twitter @SkySportsLewis. Can Southampton cause a surprise by winning at Goodison Park, something which has proved beyond Manchester United already this season, or will Everton prove too strong and strengthen their position among the early leaders? The full team news will be in shortly but who do you think are likely to be the key players?
Welcome to our minute-by-minute commentary of the Premier League clash between Everton and Southampton at Goodison Park. It promises to be a good encounter as David Moyes' side are flying high but lost to Leeds in the Capital One Cup on Tuesday, while Southampton climbed off the bottom of the table with an impressive win over Aston Villa last Saturday and then beat Sheffield Wednesday in midweek.