The final whistle goes, and Spurs enjoy their first win at Old Trafford since 1989!!
Spurs scramble the ball away, Lindegaard stays forward and eventually has a shot which is straight at Friedel.
Nani cross deflected for a corner. Lindegaard comes up.
Nani crosses but Caulker heads clear.
Hernandez comes on for Ferdinand, Dawson replaces Defoe. Intentions clear from both managers.
Wild shot from Nani goes way over the bar.
Michael Dawson and Javier Hernandez are set to come on.
Four added minutes will be played.
Defoe breaks again and shoots wildly. Perhaps he would be better trying to run the clock down.
Defoe looks to hit United on the break and although he troubles Evans, Ferdinand is back to cover.
Great chance! Patrice Evra gets between two defenders to meet Rafael's cross six yards out but directs his header too close to a grateful Friedel.
Spurs simply can't get out of their own half at the moment.
OFF THE BAR!! Van Persie's corner is flicked goalwards by Carrick and comes back of the face of the bar with Friedel and his defenders rooted to the spot.
Ferdinand forces a corner off Sigurdsson as United continue to press.
Mousa Dembele makes way for Tom Huddlestone.
Now Rooney has a sight of goal after being played in by Nani, but gets his shot from outside the box from a central position all wrong and it is way off target.
Stinging drive from Paul Scholes from the edge of the box is parried away by Friedel before Spurs clear their lines.
Another corner for United, but Spurs clear again.
Nani shows quick feet out on the right and makes space for an excellent cross which Gallas clears before colliding with the post. He is in the wars today.
Another change for United, with Danny Welbeck coming on for Kagawa.
Nani drills in a low shot from outside the box but Friedel make a good save. Not sure Spurs will be able to hold out if they continue to invite this much pressure.
United are camped in the Spurs half now, with the visitors being pushed further and further back.
Tottenham attempt to break but Defoe asks far too much of Bale, who cannot make up 10 yards on Rafael, even with his pace.
Dawson is sent out to warm up with Gallas struggling, and has something of a Balotelli moment with his training bib.
Carrick is given too much time and space to pick a cross into the box but Van Persie can only head wide under pressure.
Scholes heads goalwards from Rafael's cross, but the ball strikes a Spurs defender and the visitors clear their lines again.
Spurs make a change to try and regain control of midfield, with Gylfi Sigurdsson coming on for Clint Dempsey.
Shocking, shocking miss from Van Persie. The Dutchman is played in behind the Spurs defence on the left edge of the area, he takes the time to steady himself before dragging his shot horribly wide.
Rare attack from Spurs as Lennon looks to get away from Evans, ignoring the support from Defoe and United are able to clear.
Gallas is back on and blocks Kagawa's attempted cross behind for a corner, which comes to nothing.
Gallas is off the field briefly replacing his contact lenses.
Appeals for handball from United players and supporters as the ball bounces up and hits Sandro on the hand in the area. Foy is again not interested. No doubt it hit his hand, but he was looking away so lacked intent.
Walker heads behind to concede a corner to United. Spurs are on the ropes somewhat here.
Van Persie has the ball in the net after a delightful pass from Scholes, but the Dutchman had strayed just offside and the flag was up.
OFF THE POST!!! Wayne Rooney curls a superb effort over the wall which has Friedel beaten, only to see it come back off the post.
Poor challenge from Lennon on the edge of his own box gives United a chance to test Friedel.
Kagawa goes to ground under a challenge from Kyle Walker in the box, Old Trafford wants a penalty, but Foy - correctly - waves play on.
Rooney tries his luck from distance but Friedel is able to gather, although just for a moment it looked as though the ball might squirm away from him.
Pulsating atmosphere inside Old Trafford after an astonishing start to the second half.
End-to-end stuff here at Old Trafford! Van Persie threads the ball through the Spurs defence and the Japan international keeps his cool to beat Brad Friedel.
GOAL FOR UNITED!! Kagawa.
Just as United thought they were back in it, Dempsey is on hand to slot home after Lindegaard parried Bale's shot.
GOAL FOR SPURS!!! Dempsey.
Lovely play from United with Rafael, Rooney and Van Persie all involved before Nani pokes home.
GOAL FOR UNITED!!! Nani on target.
Wonderful long-range ball from Scholes to pick out Rooney's run into the area, but the United striker is unable to bring the ball under his spell.
Nice ball from Rooney to feed Nani out on the right, but Bale is back to slide in and concede the throw.
United start on the attack, with Carrick's ball into the area headed clear by Walker.
Rooney has slotted in behind Van Persie with Kagawa moving out onto the left.
United get the second half under way.
Immediate change from United. Wayne Rooney on for Ryan Giggs.
Andrew Gorman says: "That was a pathetic Man Utd performance - need to do better than that against a team that has looked very ordinary this year."
If you fancy backing United for a thrilling comeback, they are available at 6/1 with our friends from Sky Bet. The draw is 7/2, while Spurs are 4/11 favourites.
All of the pre-match stats (see earlier in this commentary) pointed to a home victory. Spurs are now on course for their first-ever Premier League win at Old Trafford, and their first success here since December 1989, when Gary Lineker was on target.
Gabriel Sutton writes: "Manchester United have been sluggish in the first half and I'm not sure they've had the legs to cope with the energy in this Spurs midfield. If I was Ferguson I'd have wanted to pair the experience of Scholes, Giggs or Carrick with someone like Anderson's more bullish nature. He'll have to change things at half time if he wants to cause Tottenham serious damage, bringing on Rooney wouldn't be a bad move either."
Foy brings the half to a close. A few boos from the home supporters and Ferguson has a face like thunder as he heads for the dressing room. Tottenham are full value for their lead.
Spurs take it short and United are about to clear, before a foul on Nani by Bale eases the pressure.
Another corner to Spurs after Scholes tracks back to challenge Walker.
Bale swings over another free-kick which Evra does well to deal with.
Wayne Rooney is warming up on the sidelines, while there will be three additional minutes before the break.
United keep the pressure on and Nani fires in a shot which is straight down Friedel's throat.
Nani goes down in the box after Scholes' clever flick. Vertonghen was pulling the United man back, but Foy awards a corner.
United are finally enjoying a decent spell of possession, but they need to put the Spurs defence under greater pressure.
Ferguson has come to the edge of the technical area to impart some words of wisdom to his players. They can expect a few more at the interval.
Spurs are keeping the ball with relative ease and appear to have United at arms length so far.
Corner to United, but Gallas feels it should have been a goalkick. Bale heads clear.
Evra finds some space out on the left and fires over a low cross, but it is too close for Friedel and the keeper gathers with ease.
The United supporters attempt to lift their team, but the Red Devils are second best all over the park today.
Gallas is down in the centre circle, with the physio on putting what appears to be gaffer tape all round his thigh.
Lovely finish from Bale. The Wales international received the ball just inside the United half before turning on the after-burners to leave Rio Ferdinand in his wake before firing a right foot shot across Lindegaard and into the net.
GOAL FOR SPURS!!! Gareth Bale on target.
Nice idea from Giggs after some good play from United, attempting a reverse pass through to Van Persie, but that man Vertonghen read the danger.
Van Persie and Evra link up down the left, but the full-back embarked on his run too early and the flag goes up.
Bale flights another free-kick into the box which Gallas meets, but the flag is already up for offside.
Nani attacks down the right and gets a good cross in beyond Vertonghen, but there is no-one there at the far post to take advantage.
Defoe and Vertonghen combine again with the full-back charging towards the United box once again, before the defence is able to clear.
Caulker is penalised for bringing down Kagawa on the corner of the area, but Van Persie's free-kick is headed behind for a corner.
Vertonghen has a free header seven yards out from Bale's inswinging free-kick, but the ball is slightly behind him and he can only direct it over the bar.
Crude challenge by Evra on Walker, with the United captain body-checking his opponent as he looked to burst clear. Worth a yellow card, but Foy only awards the free-kick.
Good run by Van Persie is halted by Dembele's sliding challenge.
Bale picks out Caulker with another corner to the far post, but the defender cannot capitalise and Lindegaard gathers.
Defoe picks the ball up in the centre of the field and feeds the on-rushing Vertonghen, whose first touch lets him down before Ferdinand gets across to cover.
Bale looks to have got away from his man in the centre of the park but Foy pulls the play back as he has spotted a handball by the Spurs man.
The former Arsenal man jogs back to rejoin the fray. Hopefully no lasting damage.
Van Persie is back on his feet and heading to the sidelines - hopefully briefly.
The Holland international is down after what was a heavy challenge. Van Persie needs some treatment on his ankle and could be in some trouble here.
Nani crosses into the box and Van Persie shoots wide under pressure from Gallas.
Evra looks to burst forward but is well challenged by a combination of Lennon and Sandro.
Steven Caulker climbs highest at the far post but can only head Bale's corner well over the bar.
Now Aaron Lennon has the United defence back-pedalling, with Ferdinand eventually blocking his goal-bound shot behind for a corner.
Good effort from Dempsey from outside the box has Lindegaard scrambling across his line but the shot goes just wide and the keeper had it covered.
Defoe attempts to get in behind the United defence but the assistant referee's flag goes up for offside.
Heavy challenge from Rafael on Bale leaves the Spurs winger in a heap on the edge of his own box, but he is able to continue.
Perfect start for Spurs as their possession and ball movement is rewarded with a goal from Vertonghen. The Belgium international, playing at left-back, burst into the United box as a gap opened up in front of him, before getting a slice of luck as his shot hit the sliding Jonny Evans to leave Lindegaard with no chance.
GOAL FOR TOTTENHAM!!! Jan Vertonghen via a big deflection.
Decent spell of possession for the visitors in the opening stages, with almost every player getting a touch.
Tottenham get us under way at Old Trafford.
Pre-match huddle from Spurs as kick-off approaches.
Patrice Evra and William Gallas are today's captains, with Chris Foy the match referee.
Chris Owen writes: "I'm expecting Man Utd to win 2-1 but they will need to watch out for Defoe who is on form, but RVP being the man of the match with the two for United. COME ON YOU RED DEVILS!!!"
Spurs fan Matt Levantine says: "Not looking forward to this being a Spurs fan. Be happy with a draw. Going 3-1 to Man Utd. Think Sigurdsson should be starting as well as Dawson."
United and Spurs make their way out of the tunnel and onto the playing surface for the pre-match formalities.
Kick-off is now just five minutes away, with a packed Old Trafford anticipating the arrival of the two teams.
Gabriel Sutton writes: "I think 3-0 to Fergie's men for this, with Robin van Persie to once again be the main factor in United's win. AVB has gradually got his team up and running with a couple of wins but so far they've only played relegation-threatened teams after the opening day at Newcastle. To go to Old Trafford and get something will be too much of a tall order for this Spurs team in transition. I'm predicting a man of the match display from a certain Dutchman."
Spurs subs: Lloris, Dawson, Huddlestone, Falque, Sigurdsson, Townsend, Mason.
Tottenham: Friedel, Walker, Gallas, Caulker, Vertonghen, Sandro, Dembele, Dempsey, Lennon, Bale, Defoe.
Man Utd: Lindegaard; Rafael, Evans, Ferdinand, Evra; Nani, Carrick, Scholes, Giggs; Kagawa, van Persie. Subs: De Gea, Wootton, Anderson, Cleverley, Hernandez, Rooney, Welbeck.
Our friends at Sky Bet have a host of markets on offer for today's game, with Manchester United 8/15 favourites, the draw on offer at 31/10 and Spurs available at 5/1.
Statistics will only tell part of the story, but it would be fair to say that history is not on the side of Spurs today.
Opta stat No.7: Tottenham have scored a league-high proportion of 88% of their goals in the second half this season.
Opta stat No.6: Ryan Giggs has scored more goals (10) against Spurs in the Premier League than versus any other opponent, including the first goal in this fixture in the Premier League era in September 1992.
Opta stat No.5: The last player to score a winning goal for Tottenham at Old Trafford was Gary Lineker in December 1989. Since then Spurs have lost 18 and drawn four of 22 visits.
Opta stat No.4: Jermain Defoe has scored 199 goals in his senior career and has fired in more shots on target than any other player in the Premier League this season (9).
Opta stat No.3: Tottenham have only scored eight goals in 20 Premier League visits to Old Trafford, losing 17 times and winning none.
Opta stat No.2: Wayne Rooney has scored seven goals in his last eight Premier League appearances against Tottenham and five in the last five.
Opta stat No.1: Manchester United have won 17 and lost none of their last 22 Premier League games against Tottenham.
Before kick-off, here's a few stats on today's two teams.
If you want to get in touch and have your say prior to kick-off, then you can drop me a line to email@example.com or via Twitter @skysportsrobp and I'll publish a selection of the best.
Good afternoon and welcome to our live and interactive text commentary on today's clash from Old Trafford.