Morecambe boss Jim Bentley is unlikely to make too many alterations to his squad.
The Shrimps picked up no new injury problems during last weekend's 2-1 victory at Rochdale.
Goalkeeper Barry Roche returned from an adductor strain at Spotland and came through suffering no ill-effects.
Bentley is still without left-back Robbie Threlfall (thigh), while forward Danny Carlton (knee) is a long-term absentee.
Ryan Williams signed a short-term deal with Morecambe this week having spent pre-season with Bentley's squad and the Welsh midfielder could feature if he is granted international clearance.
Having gone five games without a win, the Shrimps are unbeaten in their last three league outings to the tune of seven points.
Paul Sturrock has received a double boost ahead of Southend's trip although he is set to keep changes to a minimum after last weekend's emphatic 3-0 win at Rotherham.
Midfielder John Spicer returns to the fold having completed his three-match suspension following the victory at the New York Stadium, while centre-back Mark Phillips (groin) has trained this week and will hope to be match fit.
But manager Sturrock has admitted changes, if any, will be restricted as the Shrimpers aim to record a third successive victory.
Defender Luke Prosser is stepping up his recovery from a gluteus maximus injury but the trip to Morecambe comes too soon, while strikers Barry Corr (groin) and Neil Harris (knee) also continue to miss out.
Sturrock's plans to bolster his midfield ranks ahead of the encounter have been temporarily put on hold after his mystery loan target sustained a minor injury, with the deal now likely to go through next week instead.