David Mooney and Lee Cook are pressing for a place in Leyton Orient's starting XI after making eye-catching cameos as second-half substitutes in the otherwise disappointing 2-0 home defeat to Colchester on Tuesday night.
Midfielder Cook had missed last weekend's defeat at Oldham through illness but impressed on replacing Dean Cox against the U's and should get the nod from manager Russell Slade as the O's look to end a poor run of five defeats in their last seven matches.
However, Slade says he will be having a "body county" before the game.
Leon McSweeney has a calf problem and he, along with Moses Odubajo and Martin Rowlands are serious doubts, while Ryan Allsop, Ryan Brunt, Ben Chorley, Nathan Clarke and Jimmy Smith are also struggling.
Slade cannot call upon Kevin Lisbie, Scott Cuthbert and goalkeeping duo Jamie Jones and Lee Butcher
Striker Kevin Lisbie is thought to be a week away from returning to contention due to a hamstring strain, while defender Scott Cuthbert has a similar complaint. And goalkeepers Jamie Jones (shoulder) and Lee Butcher (knee) are still sidelined.
Coventry will assess the fitness of Nathan Cameron.
The centre-back is carrying a slight twinge after Tuesday's disappointing last-gasp 2-1 defeat at Brentford and will be monitored in the build up to the encounter.
Otherwise, manager Mark Robins boasts an unchanged squad, with fellow defender Richard Wood expected to continue despite suffering from a broken nose recently.
Robins labelled City's midweek performance as "simply nowhere near good enough" in the aftermath of a second successive defeat at Griffin Park and, ahead of another trip to the capital, has received a positive response from his players in training.
"They've come in and they've worked hard," Robins said. "There are no illusions here, there's no magic wand or a quick and easy fix. If it was an easy job everybody would be doing it.
"We've had a good spell where we had five games (unbeaten), looked like we were playing some decent football and turning a corner. But there's turning a corner and then there's obviously sport, and sport kicks you in the teeth at times. We've got to get back on the horse and start riding it again and make sure we pick up points."