Redknapp's up and out of his seat in the stands with probably mixed feelings about his new side's performance against the Red Devils, who've climbed back to the summit.
Van Persie cuts in from the left and looks to smash in United's fourth, but the cover defence is in position to deny him.
Hernandez looks to lay the ball off for Van Persie inside the area when the former should've maybe have gone for goal himself.
QPR snuffling the ball off United inside the final third with the hosts showing some spring in their step late on.
The match has entered a bit of a lull as the linesman signals four minutes of added time.
Rooney looks to crack on the pace out on the left, but he's closed down by the cover defence.
Rafael with a key header at the far post to deny QPR a late goal from the corner-kick.
No luck for the Hoops yet again as they find themselves on the ball and inside United's half of the pitch.
Mackie with a decent run down the right, but his strike at the near post is wide of the mark.
QPR not making any real movements going forward as United keep them pegged back inside their own half.
Alejandro Faurlin earns a break with Esteban Granero coming on for the closing stages of the match.
No luck for United after they earn themselves another corner-kick, but their persistence may just pay off yet again.
Hernandez looks to tee up Van Persie from the left following a lovely build-up by the Hosts, Anton Ferdinand's interception pin-point.
It's all the Red Devils right now as the Hoops do all they can to keep them at bay.
What a difference a few changes made for United, Anderson injecting some real fire into the midfield with Hernadez adding another dangerman up front.
Welbeck sees his number up in lights on the sidelines as Nick Powell checks in.
Wonderfully crafted by United, Rooney popping the ball over the defence for Van Persie to try his luck on the angle, but straight into the side-netting.
United looking to breakout from the back through Evans, who feeds Welbeck out on the right only for Shaun Derry to take him down illegally.
The Hoops on the ball and trying to slow play down, passing the ball along the halfway line.
All the play taking place inside QPR's half as the visitors struggle to get back on the front-foot.
The Hoops doing all they can to contain the Red Devils with Welbeck fancying a pop on goal from out in front.
Taarabt departs for Junior Hoilett make his appearance.
Where to now for QPR as United look to have shifted into that dangerous cruise-control of theirs.
There's no stopping them now as Anderson feeds his fellow substitute Hernandez on the quick-fire breakout, the Mexican sensation making no mistake with his first touch of the ball.
Taarabt lets rip on the run, but off-target, as a shell-shocked Hoops try to counter.
Fletcher gets in between the defence to head in another superb delivery from Rooney at the set-piece.
The Red Devils raising the tempo and shifting into a higher gear as they earn themselves another corner.
United banging on the door and QPR are doing all they can not to let them in so soon after going behind.
Fletcher turns and shoots from distance, only for the Scot to watch on as his strike soars over Cesar and the crossbar.
Tempers flaring a touch on the halfway line as the match takes an exciting turn.
Evans gets on the end of Welbeck's tap-down from the corner to put United back on level terms.
Welbeck loses possession out on the right wing; the England forward hasn't at all looked comfortable out wide.
The Red Devils turning up the heat going forward, but Rafael's slip as he sprints down the right emphasises their struggles thus far.
Armand Traore leaves the field for Anton Ferdinand to earn a run-out at left-back.
Dyer opts to go for goal with his effort sailing wide, although the better option would've been to feed Mackie out to his left.
Double substitution from United sees Young and Scholes come off with Anderson and Javier Hernandez taking to the field.
Mbia goes into the referee's book for a rash tackle on Evra.
QPR manage to keep United at bay from a corner-kick, Van Persie's delviery in the area headed clear.
Taarabt's set-piece is poor and way off target.
Poor challenge from behind on Dyer from Scholes gifts QPR a free-kick in a good attacking area.
Cisse and Mackie lead a swift counter-attack form the Hoops that the hosts just about quell.
Once again this season the Red Devils concede within the first 15 minutes after the restart and Ferguson won't be too impressed.
Mackie pounces from three yards to give QPR the lead and shake the home fans.
Cisse gets a shot away on goal, only for Ferdinand to in and intercept.
United working the ball around, but with a little bit more urgency than the first 45 minutes.
Some nifty footwork from Cesar with Rooney baring down on him saves the Brazilian at the back in possession.
A poor ball across the field for Young leaves the winger stranded trying to chase.
Long ball up for Van Persie, but the striker's flagged for offsides.
When will Fergie realise that Scholes is too old and that Young is average, every time they play we struggle against lower table teams, get Cleverley and Anderson on immediately. Philip McCarthy
Second half is underway!
There will likely be no goals until Scholes is taken off. If he remains on then it will be a 0-0 draw. At least there's no Carrick; United would be losing right now. Chris Walters
The home side remain odds on (1/3) to claim a win here, but they'll be disappointed not to have broken QPR down, with the visitors' chances of a 0-0 draw rated at 9/2 with Sky Bet. United won both fixtures against the Hoops 2-0 last season, a scoreline which is now available at 3/1 this time around.
As much as Man United want to get back to their winning ways, QPR will also want to bring their losing streak to a halt. There will be a good fight in this game. I predict 3- 1 to Man United. Kofi Ghartey
A lifelong man utd supporter from geordieland.....fergie wants to get his team playing from minute 1 not minus 1,then half of the come backs wouldnt be needed. Billie Reaveley
I was proved right last week against Norwich when I said we lose against the smaller sides. But I'm confident today of a 4-0 drubbing. Rooney (2) RVP, and Scholes grabbing the goals. Come on you reds! Jamie Warrior
Taarabt with the last shot of the first stanza, the Moroccan's curling effort straight into the arms of Anders Lindergaard.
The Red Devils desperate for the breakthrough on the stroke of half-time, but the rain seems to be dampening their best efforts.
United with the late ascendency, although their final touch is letting them down.
The Red Devils bare down on QPR's goalmouth, but the capital outfit withstand the pressure.
The Hoops pushing upfield again, only for United's defensive line to force them back.
QPR lose possession inside their half, but it's a poor shot on goal from Rooney.
Both captains called in by the referee for a discussion after an altercation between Young and Hill following the former's stumble and fall inside the area.
United now back in possession and trying to hit out on the counter.
Stephane Mbia getting into the game more down the left flank for the Hoops.
Hoops coming to live in the closing stages of the first half, with United now having to all the defending.
Mackie acrobatically heads the ball into the back of the net off Cisse's cross, but QPR's celebrations are short-lived as the linesman's flag goes up for offsides.
Rooney, again, puts Cesar to work with a shot on target.
QPR hoping to catch United by surprise, but Mackie lacks the control to keep the ball on the attack.
Rooney with a close-range shot that draws a another fine stop from Cesar, this time the Brazilian shot-stopper getting down low.
Julio Cesar does well to clear an ambitious shot on his goal.
Passes from the home side going abit wayward now as they look to be getting a bit frustrated.
United hold off a spirited surge from QPR, Ferdinand hacking the ball clear before Kieran Dyer can latch on just on the edge of the box.
The visitors admirably standing their ground as the Red Devils continue to press.
United withstand the Hoops's brief surge as they push up once again.
QPR with a half-breakout through Mackie, but he fails to feed Cisse with a decent pass out to his right.
Hoops manage to slow play down for the time being, although they don't look like making any real threat on attack at this stage.
Rooney lays the ball off for Scholes, but the veteran opts to feed Young when he should've taken the shot on the volley from out in front, the latter's effort wide of the near post.
United fail to make much of the set-piece so it';s back to grind-stone for the hosts, working the ball straight up the middle.
Another excellent ball into the area from Evra, but Clint Hill manages to head it clear with Rooney ready to pounce.
Scholes getting involved with several of the attacking movements, taking play from the centre of the pitch to just outside of the box.
Cisse holds up play as the home fans show their displeasure for the Frenchman going down with United on the attack.
Hoops with a rare touch of the ball, but it's wasted by Adel Taarabt as he drills in a weak shot from range.
Van Persie fires the ball into the side-netting after Welbeck fed the Dutch ace from the left.
Scholes, again, on the ball as he tries to feed Young with options briefly to the left and right of him.
Scholes's long ball for Young out to the right earns the hosts their first corner of the match, but they fail to threaten from the set-piece.
The Red Devils with the lion's share of possession as they spread the ball from one end of the field to the other.
Scholes goes down inside the box following an United surge, but the referee and linesmen wave play on.
Play a little stagnant at the moment with United playing the ball back when under threat going forward.
Scholes and Darren Fletcher working in unison as the two central midfielders look to build an attack.
Long ball forward for Ashley Young to chase down the right flank just has too much pace on it for the England winger.
United, once again, sitting back and putting together an attacking foray.
Paul Scholes gets away with a sloppy challenge in the middle of the park.
United camped inside QPR's half of the pitch with the visitors doing what they can to hold them off.
QPR giving away possession inside their own half, but Robin van Persie fails to make much of the opportunity.
Hoops holding their own for the time being but struggling to see much of the ball in the early stages of the match.
United slowly building from the back, but lose possession in the final third and allow Cisse to try and break out from inside his own half.
Ferdinand's right foot just slips out from under him with Jamie Mackie close at hand, but the United defender gets away with the slip-up.
Patrice Evra with a decent ball from the left for Welbeck in the area, but the Hoops defence clears the danger in time.
The Red Devils calmly working the ball around the back-four, not too fazed by QPR's chasers, particularly Cisse.
Ferguson has picked a really strong, attack line-up for today and once can already see them probing for an opening up front.
United immediately on going on the attack with Rooney feeding Danny Welbeck, the young striker trying to make a run into the box.
The match is underway!
You would be a fool to back QPR today. Ignore their failure to win this season, United want and need to get back to winning ways after Norwich. Strong line up from United. Intrigued as to why Valencia and Nani are both missing - unless I've missed something. Either way, you have to predict United to knock in at least 3. Personally, I'd predict a 5-1 home win, with a hat-trick from Wazza or RVP. Roger Clarke
Feel free to e-mail your thoughts or predictions to email@example.com and we'll publish as many of them before - and during - the game as possible.
Meanwhile, QPR skipper Park Ji-Sung misses the chance to face his former employers due to an ongoing knee issue, but Stephane Mbia is back after serving a three-match ban. Strikers Bobby Zamora (hip) and Andrew Johnson (knee) miss out, along with full-back Fabio, who cannot feature against his parent club.
United have been boosted by the return of Rooney after the England striker was passed fit following a bout of tonsillitis. Chris Smalling is also available having shrugged off a shoulder problem and takes up a spot on the bench, while fellow defender Jonny Evans starts in the heart of defence alongside Rio Ferdinand.
Manchester United are overwhelming favourites (1/6) to get three points here today, with QPR's chances rated at 14/1 as Mark Bowen and Eddie Niedzwieck take charge of the visitors at Old Trafford. We've had plenty of money on a 3-0 home win (6/1) for Ferguson's men, while Wayne Rooney has been a popular choice at 11/4 to open the scoring. Former Liverpool striker Djibril Cisse is 5/1 to score at any time, with Robin van Persie priced at 9/2 to score in the opening 10 minutes.
Working in United's favour is the recent sacking of manager Mark Hughes by the Hoops. The Welshman was shown the door at Loftus Road on Friday after he failed to pick up a single win in the first 12 games of the season. Harry Redknapp has since been named Hughes's successor, although the former Tottenham and Portsmouth boss won't be on the sidelines until next week.
A surprise 1-0 defeat for Sir Alex Ferguson's side at Norwich last weekend allowed rivals Manchester City to go top of the standings. But trailing City by just one point, and with the defending champions only in action at Chelsea on Sunday, the Red Devils can capitalise on the 24-hour advantage.
Good afternoon, I'm Devin Hermanus and I'll be taking you through all the action as Manchester United host Queen's Park Rangers at Old Trafford. Kick-off is scheduled for 1500 BST.