Wycombe's preparations have been given a blow with the news that Charlton loanee Ade Azeez has returned to his parent club for assessment on a hamstring strain.
The 18-year-old striker limped off just 25 minutes into Tuesday's Johnstone's Paint Trophy defeat at Yeovil and will be checked out by the Championship side's medical staff.
Better news for Wycombe was Marvin McCoy's return from injury at Huish Park. The 24-year-old played 90 minutes in his first appearance since the opening day of the season.
Danny Foster is ruled out of this weekend's clash with a bruised bone while Gary Doherty (back) and Anthony Stewart (thigh) are expected to return to training next week.
Matt Spring will serve the first of his three-match ban for his straight red card against the Glovers on Tuesday while Grant Basey (knee) is expected to start light running in three weeks and Matt Bloomfield (pelvic shear) is continuing his recovery.
Morecambe will be without the services of influential midfielder Andy Fleming.
Fleming misses the trip to Adams Park having collected his fifth booking of the season during last weekend's FA Cup second-round defeat to Coventry.
On-loan duo Jordan Mustoe and Richard Brodie are available once more after the Wigan full-back and Crawley forward were ineligible for cup action under the terms of their deals at the Globe Arena.
Defender Will Haining is fit and fighting for a return to the starting line-up after coming back from injury to appear as a late substitute against the Sky Blues.
Forward pair Jordan Burrow and Danny Carlton (both knee) remain on the sidelines.
Jim Bentley's Shrimps head into the contest looking to end a run of four consecutive league defeats on the road, knowing 19th-placed Wycombe will draw level with them on 25 points with a victory.