Cherries manager Eddie Howe remains without defender Miles Addison for the visit of the U's.
Addison has missed the last two games with an ankle injury, and is not expected to make a first-team return for a further three to four weeks.
Howe will also make last-minute decisions on midfield duo Marc Pugh and Harry Arter, as both face late fitness tests.
Stephane Zubar is unlikely to feature as he continues his recovery from a hamstring problem.
The Frenchman is nearing a return after over two months on the sidelines, but will not be risked on Saturday.
Bournemouth are enjoying a 12-match unbeaten run, and they will be looking to record their 10th win from their last 13 games to continue their march towards the play-off places.
Colchester are missing a trio of players through suspension.
Defender Magnus Okuonghae and midfielder Marcus Bean both received their fifth cautions of the season during the 2-0 defeat against Oldham last weekend and serve their one-match suspensions.
They join Gavin Massey on the sidelines, as the striker sits out the second of his three-game ban after being sent-off in the 5-1 defeat at MK Dons.
Defender Matt Heath and midfielder Kem Izzet have both returned to training following injury, but neither has been able to build up their match fitness after planned reserve games were called off due to the weather.
The pair could find themselves on the bench but are unlikely to be involved.
On-loan midfielder Craig Eastmond has returned to parent club Arsenal after suffering a broken foot.