The hosts will be without Kevin McDonald for the visit of the league leaders.
The midfielder limped out of last week's 3-1 win at Carlisle with an ankle injury following a heavy challenge and is yet to recover.
The Irishman is still struggling with swelling so the games over Christmas are a more realistic return date, with David McAllister primed to fill in against Rovers.
The cold weather has restricted the Blades from training over the last couple of days, so they will have to wait until Friday to assess hamstring victims Tony McMahon and Dave Kitson, with boss Danny Wilson not expecting them to be available.
Mark Howard (thigh) and Lescinel Jean-Francois (knee) are back in training, but this match comes too soon for the duo, who have both been sidelined for lengthy periods of time.
Wilson's side, who are unbeaten at home in the league this season, will go above this weekend's opponents if they can win and will top the table if Doncaster fail to beat Coventry.
"Confidence-wise it will do us the power of good if we can win," Wilson said. "But it's a tough game, Ronnie has done remarkably well."
The visitors have been rocked by the news that Ben Gibson is unlikely to feature for the rest of his loan spell ahead of their top-of-the-table clash this weekend.
Teenage defender Gibson, who has been borrowed from Middlesbrough, has been struggling with a mysterious injury for a while and did not feature in the 2-2 draw against Portsmouth on Saturday.
A specialist has subsequently discovered Gibson's injury is an abductor problem and the centre-back faces up to two months on the sidelines.
While Rovers boss Ronnie Moore concedes a few of his other players are carrying knocks, the squad is likely to be similar to the one which drew with Pompey.
There are a host of players on the sidelines, though, with captain James Wallace (knee), striker Jean-Louis Akpa Akpro (broken metatarsal) and winger Abdulai Bell-Baggie (knee) all long-term injury victims.