Chesterfield boss Paul Cook could name an unchanged side.
The Spireites have won their last four league outings and Cook will be reluctant to make too many changes.
The most recent victory came last weekend against high-flying Port Vale, to lift the Derbyshire outfit to within two points of the play-off places.
Cook has no injury or suspension worries ahead of the clash and boasts a fully-fit squad.
Midfielders Danny Whitaker and Craig Clay as well as strikers Brennan Dickenson and Jack Lester have all featured from the bench in recent weeks and are pushing for a starting role.
Victory against the Brewers could lift Cook's side into the top six for the first time this season.
Burton boss Gary Rowett has some concerns over striker Calvin Zola.
The Brewers' top scorer has been forced to reduce his workload in training recently due to a groin problem.
And Rowett has employed a 4-5-1 formation away from home of late, meaning Zola or striker partner Billy Kee would have to make way.
Kee, who scored the winning goal against Accrington last weekend, is expected to get the nod against the Spireites.
Rowett has been boosted by news that goalkeeper Stuart Tomlinson could return before the new year.
Tomlinson was expected to miss the remainder of the season with a knee injury, although the weekend will come too soon for him.
The Brewers have no other injury or suspension worries ahead of the trip.