Bournemouth are likely to be without top scorer Lewis Grabban as they look to extend their unbeaten run to 18 games.
The 24-year-old former Millwall striker, who has scored 10 goals this season, has not trained all week due to illness and is extremely doubtful to line up against Paolo Di Canio's men - who are just three points above the Cherries.
And manager Eddie Howe will decide whether to stick with Matt Tubbs and Josh McQuoid up front after the pair started in the 1-1 draw with Wigan or recall Brett Pitman in place of either of the forwards, while Wes Thomas could return to the squad.
Howe is also likely to recall David James to his starting line-up with Shwan Jalal getting the nod in the FA Cup draw, as he had in all the previous rounds.
Long-term absentees Shaun MacDonald, Darryl Flahavan and Stephen Purches remain sidelined along with Charlie Sheringham.
Swindon are set to be unchanged as the form team in Europe look for another victory against the Cherries.
Having won their last four matches by a combined score of 16-0, the Robins have a better record than the equivalent of any side in any major league across the continent.
And with new fresh injury or suspension worries Paolo Di Canio looks like he will name the same matchday squad.
Loanees Danny Hollands and Chris Martin extended their stays with the club from Charlton and Norwich respectively this week while Miles Storey is back in training but not ready to face Eddie Howe's side, now unbeaten in 17 matches.
Jay McEveley is edging closer to a return but this game comes too soon for the left-back while former Tottenham defender Troy Archibald-Henville will only face eight weeks on the sidelines following a knee operation.