Sheffield United boss Danny Wilson is expected to hand home debuts to defender Danny Higginbotham and striker Jamie Murphy.
Former Stoke player Higginbotham, who recently signed a short-term deal until the end of the season, has started in the Blades' last two games away from Bramall Lane, while Murphy completed his permanent switch from Motherwell last week in time to make his debut in the FA Cup win at Oxford.
Manager Danny Wilson has no new injury or suspension worries, but is without defenders Matt Hill (broken jaw) and Neill Collins (fractured cheekbone) for six and eight weeks respectively, while striker Shaun Miller (knee) is out for the rest of the season.
Forward John Cofie has returned to Manchester United following the end of his half-season loan spell and midfielder David McAllister this week completed a permanent move to Shrewsbury.
Goalkeeper Mark Howard (thigh) and defender Lecsinel Jean-Francois (knee) are both back in training, but not yet ready to feature as the Blades look to climb back into the top two.
Yeovil manager Gary Johnson will be boosted by the return of top scorer Paddy Madden.
Madden, who has scored 10 goals this season, was cup-tied for the midweek Johnstone's Paint Trophy area semi-final defeat at Leyton Orient but is set to return.
Johnson, who was unhappy at his side's defeat to ten-man Orient, has suggested that 'a couple' of new faces could be brought in.
And any new recruits could come straight into contention at Bramall Lane with midfielder Ed Upson being forced off with a knee injury on Tuesday while Dominic Blizzard also required treatment.
Fit-again left-back Nathan Ralph returned to action with a substitute appearance and is likely to be involved in the squad again.
However Keanu Marsh-Brown and Reuben Reid were not involved and it remains to be seen whether Johnson involves the duo against Danny Wilson's men.