Bury boss Kevin Blackwell has no new injury worries.
The Shakers' midweek meeting with Scunthorpe was postponed due to a frozen pitch at Gigg Lane and Blackwell is set to select from the same squad.
He has options available to refresh an attack that has drawn blanks in their last two outings - Andy Bishop, Nicky Ajose and David Healy could all come in contention to start, while on-loan Peterborough youngster Jonson Clarke-Harris is gunning for a place in the matchday squad once again.
Midfielder Tom Soares (hamstring) will struggle to feature before the end of the season, while defenders Phil Picken (knee) and Adam Lockwood (groin) and midfielder Shane Byrne (blood infection) must wait until next term.
Colchester are again likely to be without Tom Eastman and Freddie Sears.
Defender Eastman missed Tuesday's 2-2 draw at Coventry with the knock sustained early on in last weekend's defeat to Crewe, while striker Sears sat out of his third match in succession with a troubling knee problem.
Both are set to be absent once more at Gigg Lane while striker Jabo Ibehre also serves the final game of his three-match suspension.
Left-back Bradley Garmston shrugged off a knee complaint to start at the Ricoh Arena and should again be involved.
Manager Joe Dunne admits he may have to look at rotating one or two for what he expects will be a "toe-to-toe street fight" against Bury, with some of his side running on empty as they bid to secure League One survival.