Carlisle's latest signing Mathieu Manset is hoping international clearance issues will be resolved in time for him to make his debut against the Glovers.
The ex-Reading forward had hoped to be involved in last week's defeat at Leyton Orient, but former club FC Sion have so far refused to hand over his registration.
Scottish striker Lee Miller is available again after sitting out a three-game ban for his recent red card at Notts County and is hoping to go straight back into the starting line-up.
The Cumbrians will be without suspended goalkeeper Mark Gillespie following his dismissal for two yellow cards in midweek, so Adam Collin will make his first start since early December.
Manager Greg Abbott has hinted he may go without a substitute goalkeeper on the bench as the Cumbrians chase only their second win in nine league matches.
Yeovil will be without captain Jamie McAllister when they make the long trip to Carlisle looking to get back to winning ways.
Glovers boss Gary Johnson was disappointed with his side's display in their televised 2-0 defeat to Swindon on Tuesday night, a performance which deteriorated after the loss of their captain.
McAllister, who had been having painkilling injections in his ankle in recent matches, limped off four minutes after half-time but he had already picked up his 10th booking of the season which rules him out of Yeovil's next two matches.
"We had to give him a rest anyway, he had been having these injections and we knew we would have to give him a rest for the next couple of games and he has that anyway now with the 10th yellow card," Johnson said.
"We will have to deal without him which is a shame as without him we don't seem half the team."
One player who will now walk a disciplinary tightrope is Byron Webster who looks likely to feature despite being on nine yellow cards, one away from joining his captain in the stands.