Bristol Rovers will be without captain Tom Parkes.
Parkes is suspended after picking up his 10th yellow card of the season in the 4-2 win over Dagenham on Monday and that means a first start for Port Vale loanee Clayton McDonald.
They will also be without influential midfielder John-Joe O'Toole who has returned to Colchester after the end of his loan spell.
Goalkeeper Steve Mildenhall will return to training in the build-up to the match and is expected to play after missing Monday's clash with an ankle injury sustained during the warm-up.
John Ward says his players must aim to finish the season inside the top half of the table, a real achievement considering Rovers were bottom on Boxing Day.
Sammy Moore is poised to return to the AFC Wimbledon squad for the trip.
Moore missed both of the Dons' fixtures over Easter - which both ended in 1-0 defeats - through illness but is back in training.
However, fellow midfielder Peter Sweeney is set to sit out again as he recovers from a foot injury.
Jim Fenlon remains sidelined by a back problem but Curtis Osano has overcome his recent calf injury and Huw Johnson is fit after a groin problem
Experienced striker Gary Alexander will be pushing for a return to the starting line-up after dropping to the bench for Monday's defeat by Barnet.
Midfielder Harry Pell will be lining up against his former club.