Sheffield United's new manager Chris Morgan will take charge of his first game and is boosted by the return from suspension of defender Tony McMahon.
McMahon sat out a two-game ban after reaching 10 yellow cards for the season and Morgan must decide whether to put him straight back in at right-back in place of Matt Hill.
Morgan has recalled Jordan Chappell from his loan spell at Torquay. The young winger played regularly for Morgan in the Blades Under-21s side and could make his first senior league appearance for the club.
Teenager Callum McFadzean is still pushing for his first start after another substitute's appearance in the home defeat to Crawley on Tuesday and fellow midfielder Barry Robson could also return.
The Blades, who have no other new injury or suspension worries, are chasing their first win in four matches as they look to close the gap on the top two.
Swindon boss Kevin MacDonald will be forced into one change.
Midfielder Dean Parrett, 21, has returned to parent club Tottenham after his loan spell was terminated early. The player joined until the end of the campaign but was sent back during the week after making three appearances.
Adam Rooney is among the candidates to take Parrett's place in the side as the Robins look to end a four-game winless run.
They do so without Nathan Thompson, James McEveley and Tommy Miller. Defenders Thompson (ankle) and McEveley (knee) are unlikely to feature again this season, while striker Miller (calf) is yet to return to training and will sit out at least another week.
Swindon have fallen eight points behind the automatic promotion places and could drop out of the top six if they suffer a third successive defeat.