Shane Cansdell-Sherriff is set to return to the Preston defence.
Cansdell-Sherriff missed out on Tuesday night's 4-2 Johnstone's Paint Trophy win over Morecambe following his red card against Oldham last weekend.
Akpo Sodje is expected to return to Graham Westley's starting line-up after coming off the bench to bag a brace at the Globe Arena.
Fellow forward Lee Trundle (knee) remains on the sidelines along with winger Lee Holmes (gashed leg).
Westley hopes his players can embrace an occasion he believes cannot be treated like any other game.
"You can never say that being on the TV is just another game, because players will think about the cameras and if players are thinking about it, you'd be daft to ignore it," he told Preston's official website. "But, at the same time, you are just playing for three points."
MK Dons defender Antony Kay will miss out.
Kay will be suspended for the trip after after picking up his fifth yellow card of the campaign during his side's 2-2 draw with Portsmouth last Saturday.
The npower League One promotion hopefuls were rocked this week with the news that fellow defender Gary MacKenzie is expected to be out for three months after being told he faces hip surgery.
The Scot, 26, has not played since a 1-1 draw with Notts County in September.