Rochdale are hopeful new signings Ian Craney and Ray Putterill will be registered in time to face Barnsley.
The pair have been training with the first team throughout the club's pre-season preparations and have joined on non-contract terms after impressing manager John Coleman.
Dale will, however, be without reserve goalkeeper Matthew Edwards, who is ruled out with a wrist injury.
Edwards is joined on the sidelines by Reece Gray after he suffered an horrendous leg break in pre-season, dislocating an ankle, fracturing a tibia and snapping medial ligaments in a behind-closed-doors fixture.
Better news from Coleman is that summer signings Dele Adebola, Phil Edwards and Matty Pearson are all available, as is new club captain Peter Cavanagh.
Barnsley will be without injured trio Mido, Tony Silva and Luke Steele as boss Keith Hill returns to his former club.
Striker Mido could be out for up to 15 weeks after he suffered a ruptured hamstring in pre-season while fellow new signing Silva (knee) limped off in the friendly draw at Doncaster.
Goalkeeper Steele, who is the Tykes' reigning player of the year, is sidelined with an abdominal injury carried over from the last campaign.
Former Tottenham keeper Ben Alnwick could make his debut in the absence of Steele with Polish midfielder Tomasz Cywka also looking to start the season well after moving from Reading.
Defender Scott Golbourne is likely to miss out through injury but midfielders David Perkins and Stephen Dawson should be in contention for the trip to Spotland.