The Germans, last season's runners-up, have recorded 15 wins from their previous 16 home European ties and head into Wednesday's match on the back of an impressive 3-0 win in Hamburg, which maintained their lead at the top of the Bundesliga.
After suffering a shock 3-1 loss at BATE Borisov on matchday one, Heynckes' men will be targeting maximum points to take full advantage of the meeting between the Belarus side and Valencia at Mestalla.
"I expect more from the team. We have achieved nothing yet," said the coach, whose side sit third in Group F on goal difference. "We must ignore all the praise which is coming over us, especially since our victory in Hamburg.
"There are no easy opponents in the Champions League."
After being beaten 1-0 at home by Bayern a fortnight ago, Lille's hopes of qualification for the Europa League even now looks out of reach following their three successive defeats, which leaves them bottom of the group having come through the play-offs.
But coach Rudi Garcia insists his side will take a positive approach, saying: "Tomorrow, it will be important to believe in our chances, and the players are convinced that they can get a result."
Arjen Robben is set to return for Bayern following his injury lay-off, but striker Mario Mandzukic is doubtful after missing training with a virus.
With Mario Gomez still missing with an ankle injury, Mandzukic's most likely replacement is Claudio Pizarro.
Defenders Franck Beria and Mathieu Debuchy (both calf) and Marko Basa (hamstring) will undergo late fitness tests for Lille.
The trio join Idrissa Gueye and Ryan Mendes (both ankle), Lucas Digne (meniscus) and Adama Soumaoro (back) on the sidelines.