Manager Neil Lennon has been rocked by injury problems ahead of Wednesday's eagerly-anticipated Group G clash at Celtic Park.
Izaguirre is out for six weeks with a hamstring injury picked up during the 2-2 Scottish Premier League draw with Dundee United on Sunday and stopper Thomas Rogne is out for two weeks with a calf complaint picked up in the same game.
Winger James Forrest (hamstring) and strikers Gary Hooper (hamstring), Lassad (groin) and Georgios Samaras (ankle) missed the trip to Tayside and only the latter appears to have a real chance of making the game against the Catalan giants.
Barcelona defender Gerard Pique has been given the green light to return to action after injury and has been included in the Catalan side's squad.
Pique has not played since suffering a foot injury against Spartak Moscow on 19th September but is now available again for coach Tito Vilanova.
Pique's central defensive partner Carles Puyol is still missing through injury though, as are Adriano and Thiago Alcantara, while Sergio Busquets is suspended.