Torres was hauled off during Saturday's Premier League defeat at West Brom after another miserable performance and Di Matteo could start Daniel Sturridge or Eden Hazard in his place in Turin.
Ashley Cole should return after recovering from his hamstring injury, as should several other rested players but John Terry (knee) and Frank Lampard (calf) were left in London.
Juventus are sweating on the fitness of Mirko Vucinic, who has been battling flu-like symptoms.
However, the striker trained on Monday afternoon and a late decision will be made on his fitness.
The Italian champions are expected to line up in a 3-5-2 formation, with Fabio Quagliarella, Alessandro Matri and Nicklas Bendtner vying to partner Sebastian Giovinco if Vucinic fails to make it.