Full Time. That's it. City battled hard after the break but it finishes 1-1 and they are eliminated from the Champions League with a game to go. Real Madrid go through with Borussia Dortmund.
90+5 Garcia booked.
Tevez nearly latches onto a through-ball but misses the connection as the ball drops over his shoulder.
The ball sits nicely for Toure on the edge of the box but he skies the shot.
There will be five minutes added time.
90 Albiol on for Di Maria.
88 Milner on for Aguero.
City pushing for that winner but they are running out of time to keep their Champions League hopes alive.
Quality first time cross from Maicon and Coentrao has to concede a corner.
Good interplay from City and Tevez fires off a shot from the left edge of the box but Casillas saves low to his right.
Real keeping the ball with 10 men now but when the cross comes in Hart is there to claim.
Ronaldo running at four defenders and is bodychecked by Kompany but the referee is still unimpressed. Some strange decisions this evening.
Delay as Kompany is down injured.
Silva does brilliantly to get away from Pepe and finds Dzeko in the left channel but the Bosnian fires his cross-shot with his weaker foot over everyone in the box.
City pushing for the winner now. And then Ronaldo tries to break but sees his shot deflected safely into the hands of Hart.
Ten-man Real Madrid are now 10/11 to earn a draw against City, with the home side 15/8 to win. Jose Mourinho's men are 9/2 to seal victory with 15 minutes to go.
75 Varane on for Benzema as Real try to hang on. Some turnaround.
73 Goal! Sergio Aguero slots the ball to the left of Casillas and sends the keeper the wrong way.
73 Arbeloa gets a second yellow card.
73 Penalty! Arbeloa with a foul on Aguero. Another soft decision but what a chance for City.
It was a lunging challenge from Silva and he got the ball first but then caught Benzema on the ankle with the follow through.
Scrappy game now with a lot of stoppages. Benzema is down at the moment.
68 Callejon on for Modric.
Ronaldo gets a shove from Kompany and stops abruptly but the referee gives nothing to the delight of the crowd.
And that's when they are nearly punished. Ronaldo with a dipping shot that Hart cannot hold and the Portuguese forward nearly gets to the rebound first but City clear.
City really giving this everything now.
Chance! Maicon's cross is deflected and it seems easy for Aguero at the far post but Casillas saves brilliantly on the line and Real clear. Should be all-square here.
Silva's free-kick hits the wall. Khedira is struck on the temple and play stops.
61 Booking for Ramos now for handball. Last few cards have been very soft.
60 Tevez on for Nasri.
Arbeloa seems to be grabbed by Garcia and goes down but nothing given.
58 Zabaleta booked for a foul on Di Maria. Harsh as he got the ball first.
Wide-open game now. Ronaldo springs the offside trap on the left and has time to pick out the head of Khedira at the far post. He heads down but doesn't get enough on it. Chance spurned.
Chance for Real to break as they have four on three but Di Maria chooses the wrong option. At the other end, Silva's weak shot is straight at Casillas.
53 Nasri frustrated to give the ball away and leaves his studs in on Modric. Booking.
Coentrao does well on the left to get to the byline but Nastasic clears the cross.
The crowd are getting involved now. Good chance to overload on the right but Dzeko and Silva both misplace passes. The Silva wriggles free and the ball finds Aguero who can run through on goal. But the forward's touch is poor and Casillas can force the ball away.
Maicon with a good cross for Aguero who is free at the near post but gets his header all wrong.
48 Alonso booked for a foul on Spain team-mate Silva.
The corner comes to nothing but City do retain possession. Bright start after the break from the home side.
Maicon hangs a cross under the bar and Dzeko challenges with Casillas. The keeper isn't happy but not a lot in it. Corner to City.
Real Madrid kick-off and we are underway in the second half.
46 Garcia on for Kolarov.
Half Time. That's the end of the first half. Real Madrid are a goal up through Benzema and could have scored more in the early stages but didn't find a second and Manchester City are still clinging on in there.
Benzema with a shot well over the bar from distance. Real finding it tougher to get close to the City goal now though as we approach the interval.
Cross from the right nearly finds Benzema at the second attempt but Hart claims.
40 Maicon booked for pulling down Benzema.
Ronaldo threatens to break and is running at the City defence but Aguero has tracked back to tackle. Brilliant from the Argentine forward.
Scrappy passage of play. City keeping the ball better than they were though and the Real counter-attacks have dried up a little. No sign of an equaliser though.
City looking a little happier with a back-four and well in this game now.
Kolarov hits the free-kick but it curls wide of the post.
32 Arbeloa booked for pulling at Aguero's shirt.
Silva does well to get away from two challenges on the right and cut the ball back to Dzeko but the big forward is off balance and his left-footed shot balloons upwards.
29 Toure booked for a lunge at Ronaldo.
Maicon shows what he can do at the other end with a surging run and one-two before toe-poking just wide of the post.
Gary Neville on Sky Sports points out that City have switched to a back-four now with Zabaleta having gone from the right of a back-three out to left-back. Suggests Mancini acknowledges the early tactical battle has been won by Mourinho.
One-two from Benzema on the edge of the box before he takes a wild swing and scuffs the ball with his left foot. The pace of this game is astonishing.
Chance! Khedira gets away from two and is through one-on-one with Hart. For some reason the midfielder delays and Hart is off his line to smother. Should have scored but instead City break through Aguero and his cross is put behind for a corner that Casillas claims. Cracking game.
Coentrao with a lofted pass but Benzema is offside.
Casillas punches the corner clear.
First effort from City. Aguero turns Arbeloa and Casillas has to turn over his curling shot.
Pepe's header is saved by Hart.
Fast break from Real is devastating. Di Maria runs away from Toure - no easy task - and then crosses for Ronaldo who lays the ball off to the advancing Modric. His shot is blocked for a corner.
Better possession from the home side as they look for an opening.
Five shots on target already from the visitors. City still waiting for their first effort on goal of any description.
Chance! Ronaldo beats the offside trap and lobs Hart. But Nastasic is back on the line to clear... only as far as Ronaldo. He has another chance and shimmies past Hart only to see the keeper get enough on the shot to deflect it wide of the post for a corner. That comes to nothing and City recover. They are being completely outplayed at the moment.
Ronaldo is enjoying himself now. Skins Kompany not once but twice. He then crosses for Khedira at the near post but the Germany international gets too much on the header.
Ronaldo has Maicon and Zabaleta for company but he still gets a cross in. Khedira opens up his body as the ball comes across but his side-footed effort skews wide.
Maicon not endearing himself with that cross either. Straight into the arms of Casillas.
Horrible defending from Maicon. Di Maria curls the cross in from the right and Benzema has pulled onto Maicon at the far edge of the area. He drifts in completely unmarked and slots the ball past Hart from close range.
10 Goal! Karim Benzema!
Lightning break by Real but Benzema cannot quite get away and has to cut inside. Ronaldo fuming that Zabaleta is not being punished for a clear foul in the build-up.
Confusion in the Real defence and Silva has the chance to shoot from distance but checks the shot and tries a through-ball that is blocked.
Real beginning to get their foot on the ball. Coentrao beats Maicon but his cut-back is intercepted.
Casillas punches away.
Khedira fouls Kolarov. Chance for City to cross.
When Real do look long, Benzema is offside.
No goalmouth action in the early minutes. The battle is in midfield with Toure prominent.
Dzeko does well to bring the ball down with his chest but Ramos recovers to put in a crunching challenge.
Boos for Ronaldo.
Positive start from the home side as they win possession in the Real half. But Kolarov's cross isn't a good one and the visitors can break.
City kick-off and we are underway.
Thanks for your feedback. The players are emerging from the tunnel and we'll be underway shortly.
Ryan: "I fancy City to be absolutely demolished tonight. 4-1 is my prediction."
James has a bold prediction: "6-0 to Real Madrid with Ronaldo to score a hat-trick and on the third goal, take off his jersey to reveal a United one underneath!"
Jack: "I think this is going to be a difficult game for Madrid but I still see them winning the game with Ronaldo getting two goals and Kolarov getting a lone goal so my prediction is 1-2 to Madrid but it's going to be a difficult game for them."
Akshet: "Close game but Madrid are always the favourites to win any game. Hart will be key to keeping City in the game but it won't be enough. 3-1 Madrid. Tevez, Ronaldo, Benzema and Ramos with the goals."
Marc says: "Interesting to see Modric start."
Caylan: "Manchester City 1 Real Madrid 3 is my prediction."
But they'll need to remain vigilant late on as 60% of Real Madrid's goals have been netted in the final 15 minutes of games (including all three in their opening match against City); a competition high proportion.
City will fancy their chances of scoring tonight. Real Madrid have kept just one clean sheet in their last 10 Champions League games.
As for that man Ronaldo. He has scored 15 goals in his last 13 Champions League appearances and has netted in four of his last six appearances against Manchester City.
Only two teams have ever had two points or fewer after four match days and qualified for the next stage (Lokomotiv 2002-03 & Porto 2004-05).
Steve says: "Mancini needs a result here so badly you can almost hear those teeth grinding. Kolarov can be a big player tonight and goals are certainly on the cards. I fancy a 2-2 draw and another early exit. Sorry Roberto!"
There you have it. People all over the world following this one tonight.
Farah: "Greetings from New Dehli, India. Everyone over here is looking for City to qualify as we think that the City manager is a great man. We are a bit nervous and concerned as we not only have to score but we also have to stop world-class players in Real Madrid from scoring."
Ian: "Hope you don't mind an exiled blue living in Spain. I am going for 2-1 win for my beloved blues tonight. There has been a lot of hype about Ronaldo but the Etihad has not been a happy hunting ground for the Portuguese primadonna. He has played five times there, scored once and been sent off twice."
Jamie: "It's got to be 3-2 Real Madrid. Ronaldo 1st goal. Come on Madrid!!"
Any thoughts or predictions ahead of this one? Let me know by email at firstname.lastname@example.org or on Twitter @GhostGoal.
Our friends at Sky Bet have the odds for this one. They make Real Madrid favourites at 6/5 with Manchester City at 2/1. The draw is available at 27/10.
Manchester City: Hart; Zabaleta, Kompany, Nastasic; Maicon, Nasri, Toure, Silva, Kolarov; Dzeko, Aguero.
Real Madrid: Casillas; Arbeloa, Ramos, Pepe, Coentrao; Khedira, Alonso; Di Maria, Modric, Ronaldo; Benzema.
The teams are in and will be up shortly.
But the Portuguese coach does acknowledge that City can be a threat in a one-off game and Roberto Mancini could really do with showing everybody he knows what he's doing in Europe.
Real Madrid boss Jose Mourinho has already written off the Premier League champions' hopes of qualification from Group D.
City need to win here and in Dortmund in their final game as well as hope results elsewhere go their way if they are to qualify.
Welcome to live commentary of Manchester City versus Real Madrid in the UEFA Champions League.
Kick-off is 1945 GMT.