Leyton Orient will still be without Kevin Lisbie in their rearranged encounter.
Striker Lisbie suffered a hamstring injury against Sheffield United last weekend and could be out for another three weeks.
Centre-half Scott Cuthbert remains on the sidelines with his hamstring problem while goalkeepers Jamie Jones (shoulder) and Lee Butcher (knee) are also long-term absentees.
Winger Scott Wagstaff should keep his place after making his debut in Saturday's 2-0 defeat at Bournemouth following his loan switch from Charlton last week.
Ryan Brunt and Lloyd James shook off knocks to make the bench at Dean Court and should be involved again while Leon McSweeney will be facing the club where he made 88 appearances in two years before joining Orient.
Hartlepool defender Evan Horwood and on-loan striker Charlie Wyke are both major fitness doubts.
Horwood was forced off nine minutes before half-time in Saturday's home draw with Doncaster with a heel injury, while Middlesbrough teenager Wyke, a second-half substitute, sustained a nasty gash nine minutes from time that later required stitches and is also struggling to make it.
Skipper Sam Collins, who has started on the bench in the last four matches, could be recalled to the starting line-up if Horwood is ruled out.
Manager Neale Cooper is still without midfielder Andy Monkhouse, sidelined for six weeks with ankle ligament damage, but has no other new injury or suspension worries.
Midfielder Simon Walton and striker James Poole are pushing for recalls to the starting XI and another forward, teenager Luke James, could return to the squad following a thigh injury.
Pools, second from bottom in the table, are chasing their first win in nine league matches.