The stalemate made it five draws in seven Premier League matches by Tony Pulis' men, while a point will be scant consolation for Reds manager Brendan Rodgers.
It could have been worse for the hosts, who twice almost pushed the self-destruct button, but ultimately this will be viewed as another disappointment in a stop-start season.
Rodgers made eight changes from the side beaten by Udinese on Thursday, after which he called his players "lazy", and one of his targets, Stewart Downing, was not even on the bench.
Liverpool had been on the receiving end of a kicking from their manager in midweek, and got another one at Anfield at the hands of Stoke, who took their renowned physical approach across the line of legality on plenty of occasions.
But if Liverpool were keen to escape the sharp edge of their manager's tongue, they hardly helped themselves.
Twice, goalkeeper Jose Reina attempted to pass the ball out to a midfielder; twice, Stoke scented a weakness and pounced, and twice it was only the reactions of the Spaniard which saved Liverpool.
Stoke had clearly anticipated Reina would refuse to launch the ball long, and the first time it was Nuri Sahin who conceded possession, giving Charlie Adam a chance to humiliate his former employees. The Scot advanced toward goal, but Reina was quickly out of the blocks to narrow the angle and parry the shot.
Liverpool committed the same mistake again soon afterward. This time it was Steven Nzonzi snapping into the challenge as another Reina pass went awry and Michael Kightly tried to flight the ball into the goal, but the keeper recovered to turn it over at full stretch.
Having passed up those chances, Stoke reverted to type, striking long balls and stopping their opponents by foul means as often as fair, and the game disintegrated as a spectacle.
Liverpool's frustration increased, while the away fans chanted 'You're not famous any more', and all that there was to give the Reds fans some hope before the break was a sweeping shot by Steven Gerrard turned aside by Asmir Begovic, and a toe-poke from Daniel Agger that bounced wide.
Proper football threatened to break out in patches in the second half, as Stoke toned down their challenges, and it was Liverpool who had just about all the chances, although none were clear-cut.
First, a terrific combination between Gerrard and Luis Suarez was just thwarted. Gerrard then picked out Glen Johnson's run with a pass of arrow-like precision, but his England team-mate, on the run, could not keep the shot down.
A run of genuine brilliance by Suarez, the most gifted person on the pitch by some distance, nearly brought a superb goal, but he just bent the shot wide of the angle.
Raheem Sterling was presented with perhaps Liverpool's best opportunity after Agger's driving run, but he tried to drill it inside the near post and only found the side-netting.
Suarez then showed the best and worst of his talents in the space of a couple of minutes, first with a dive in the penalty area that was embarrassingly obvious, then bursting down the right and powering a shot against the outside of a post from a tight angle.
Martin Skrtel nearly snatched a winner at the end when he hooked Joe Cole's ball back across goal, but it dropped, agonisingly for Liverpool, the wrong side of the post.
A dreary goalless draw at home will hardly provide much succour for Rodgers - and Michael Owen, missing an Anfield return due to injury, can only be thankful he was not playing.