Lee Hughes and Jamal Campbell-Ryce will come straight back into Notts County's starting line-up.
The pair have missed the last three games through suspension, but are set to earn an immediate recall with Chris Iwelumo and Alan Judge both absent.
Iwelumo, on loan from Watford, has not been made available for the game, while midfielder Judge is serving a one-match ban after picking up his fifth yellow card of the season in the goalless draw at Yeovil on Saturday.
Julian Kelly, Hamza Bencherif, and Francois Zoko all lost their starting places against the Glovers, and look set to be made to continue their spells on the bench against the Millers.
Defender Manny Smith made a return to action for the reserves following four months on the sidelines with a knee problem, but is unlikely to feature.
Andre Boucaud, Jordan Stewart, and Tom Williams continue to be ruled out through injury meanwhile.
Rotherham boss Steve Evans is likely to be without the services of skipper Ian Sharps.
The defender left the field after just 18 minutes of Saturday's defeat to Gillingham after suffering a broken nose in a clash with former Millers striker Deon Burton.
Jack O'Connell replaced him on the day and is likely to deputise again, while Nicky Hunt also provides further options at the back.
Striker Kieran Agard returned to the bench in that fixture after recovering from a thigh injury and could be in line for a starting place.
Midfielder Mitchell Rose also comes back into contention after serving the final game of his three-match ban at the weekend.
Evans has no new injury or suspension worries, but goalkeeper Scott Shearer (knee), defenders Dale Tonge (ankle) and Craig Morgan (foot) plus midfielders David Noble (hamstring), Kari Arnason and Lionel Ainsworth (both shoulder) remain sidelined.