Gillingham could hand a debut to Anton Robinson for the visit of the Chairboys.
The midfielder has arrived on-loan from Championship side Huddersfield until the end of the season and is expected to be named in the matchday squad.
Leon Legge will continue in the defence after he signed permanently on deadline day. His loan spell came to an end after Tuesday night's 2-0 win over Northampton.
Cody McDonald marked his full debut with the opening goal in that midweek victory, to take his tally to two goals in as many games since joining on loan from Coventry.
He is set to partner Deon Burton in attack once more.
Wycombe boss Gareth Ainsworth has been boosted by the extended stay of loanees Michael Harriman and Bruno Andrade ahead of their trip to the league leaders.
Defender Harriman, 20, will now stay with the Chairboys until the end of the season after an agreement was reached with parent club QPR.
Andrade, also borrowed from the Hoops, has signed on at Adams Park until the end of the campaign.
Striker Matt McClure should return having missed their last match against Dagenham due to the birth of his daughter.
Ainsworth has no fresh injury concerns but he will be without Gary Doherty once again as he recovers from back surgery.
Danny Foster also went under the knife and is ruled out while Leon Johnson still has a knee injury.