Dean Cox could return to the Leyton Orient starting line-up.
The winger shook off a thigh injury to make a late appearance as a substitute in Saturday's 2-1 win over Notts County at Brisbane Road.
Boss Russell Slade must decide whether to hand Cox a recall or stick with the side which ended County's 22-game unbeaten run away from home.
Centre-half and club captain Nathan Clarke is edging closer to a return after after two months out with an ankle injury but the match will come too soon for him.
Striker Kevin Lisbie is also set to miss out again with the hamstring injury which has kept him on the sidelines for the O's last five matches.
Swindon will be without Danny Hollands as they look to extend their unbeaten run to eight games.
The on-loan Charlton midfielder has been ruled out for six weeks after picking up a fifth metatarsal stress fracture in the 2-0 win over Shrewsbury.
Manager Paolo Di Canio is keen to extend Hollands' stay at the County Ground as he sees his experience as a crucial factor during the run-in.
Young striker Miles Storey looks likely to miss out with a hamstring injury while captain Alan McCormack is set to start at left-back despite Jay McEveley returning to action against the Shrews.
The former Blackburn defender played for the final 10 minutes of the match after recovering from knee surgery which had ruled him out since early December.
McEveley's involvement came due to a slight hamstring injury to Joe Devera but the 25-year-old is available again.
Former Tottenham defender Troy Archibald-Henville is still sidelined following a knee operation and treatment.