Oldham begin life without Paul Dickov for the visit of the Glovers.
Dickov stepped down as Latics boss on Sunday having presided over eight defeats and one point from the past nine league matches, a run that leaves them hovering precariously over the relegation zone.
Youth team coach Tony Philliskirk has been placed in temporary charge for the Glovers clash and is set to select from the same squad that went down 3-1 at Walsall on Saturday.
Captain Dean Furman is due back from international duty with South Africa in the African Nations Cup on Monday but will be assessed for fatigue.
Wide midfielders Cristian Montano and Youssouf M'Changama remain out with respective thigh and medial knee ligament injuries.
Matt Smith (shoulder) and Robbie Simpson (hamstring) are also absent in attack, where on-loan Southampton striker Lee Barnard marked his debut with the opening goal at the Banks's Stadium.
Yeovil will be without the services of Middlesbrough loanee Matty Dolan.
The 19-year-old had only just agreed to extend his stay at Huish Park for a further month when he sustained an ankle injury against Brentford.
The midfielder limped off in the first half of the 3-0 victory and will now return to the Riverside for treatment.
Joe Edwards could come into the side as the Glovers look to build on their impressive victory over Uwe Rosler's men against the Latics.
Yeovil have won their last five games and sit on the verge of the League One play-off places.
"We have almost got ourselves right in the mix, but not quite as we are not above that line," boss Gary Johnson told the Western Gazette.
"Every game we go into, I'm confident in that group of lads that they are going to compete and show that desire that's needed to get into that play-off spot."