The QPR loanee is struggling with a stomach injury but will be assessed over the next couple of days to see if he can lead the line against Rovers.
Benik Afobe has returned to parent club Arsenal after suffering a serious knee injury while James Henry (knee) is also missing, with Martyn Woolford cup-tied.
Leon Best is in line to make his first Blackburn start for Michael Appleton's side.
Best, who suffered cruciate knee ligament damage shortly after a £3million summer move from Newcastle, made his long-awaited Rovers debut from the bench during the closing stages of Tuesday's night's 1-0
Championship defeat at Bolton.
The Republic of Ireland international appears set to partner Jordan Rhodes in attack as DJ Campbell is cup-tied.
Campbell's fellow loanees Cameron Stewart and David Jones are also unavailable, meaning Josh King and David Dunn could be named among the substitutes despite only returning to training on Friday from respective hamstring and calf problems.