Fleetwood will be without defensive pair Stephen Jordan and Alan Goodall for the visit of Scunthorpe.
Both players have been ruled out with groin injuries leaving Graham Alexander with a selection issue at full back.
However midfielder Gareth Evans will be available having returned to training this week after overcoming an ankle problem.
Steven Schumacher and Jon Parkin will also be pushing for a return to the starting XI after dropping to the bench for Friday's 2-0 defeat to Southend.
Scunthorpe teenager Hakeeb Adelakun is hoping to make his first start for the club at Fleetwood.
The 17-year-old made his first senior appearance in Saturday's home defeat to Exeter as a second-half substitute following injury to midfielder Sean McAllister.
McAllister remains doubtful for the club's first visit to Fleetwood having sustained an ankle injury, while striker Chris Iwelumo is still struggling to shake off the illness that kept him out at the weekend.
Skipper Michael Collins is closing in on his first appearance since late August following a knee injury and defender Christian Ribeiro, back on the bench on Saturday, is hoping to make his comeback after a groin problem.