Bees boss Uwe Rosler could name an unchanged side for a third consecutive game as the Bees prepare to host the Posh.
Saturday's 0-0 draw at Wolves brought an end to a run of five League One wins on the bounce for the London club but a return to winning ways would see them leapfrog Posh into third in the table.
Rosler could choose to freshen up his team as a busy Christmas period beckons and, should he do so, Will Grigg and Toumani Diagouraga will be hoping for starting places having featured prominently from the bench in recent games.
However, the Bees will need to improve upon their recent record against Peterborough if they are to claim a top-three place having won just once in their previous 13 in all competitions.
Peterborough will give a fitness test to top scorer Britt Assombalonga before travelling to Brentford.
Assomablonga missed Saturday's home defeat to Stevenage - a fourth straight League One loss for Posh - with a thigh injury and the 10-goal striker will have the problem checked on Tuesday.
Craig Alcock is a fresh injury absentee after coming off in the 29th minute against Stevenage and he will join fellow defender Nathaniel Knight-Percival and midfielders Danny Kearns and Joe Newell on the sidelines.
Ahead of the game, Posh boss Ferguson said: "I enjoy situations like this. I enjoy the challenge of trying to turn my team's form around. We have a lot of doubters now, and I fully understand why, but every team will have a bad run at some stage of the season."