Leaders Leyton Orient will be without David Mooney and Elliot Omozusi through suspension when they host Crawley.
Striker Mooney is halfway through a three-game ban following his sending-off in the FA Cup win over Walsall a fortnight ago and full-back Omozusi sits out one match after collecting his fifth booking of the season at Bradford last weekend.
Gary Sawyer is likely to step into the back four in Omozusi's absence while Mooney's strike partner Kevin Lisbie is poised to return to the starting line-up.
Lisbie came on for the final 17 minutes in the 1-1 draw at Valley Parade after recovering from an ankle injury.
Crawley will be without captain Josh Simpson when they head to leaders Leyton Orient.
Midfielder Simpson suffered a hamstring tear in the warm-up at Bristol Rovers a fortnight ago and is not expected back until the new year.
Veteran striker Gary Alexander will be hoping for a recall against his former club after dropping to the bench for Wednesday night's FA Cup replay against Rovers, which had to be abandoned after 75 minutes due to a waterlogged pitch.
Boss John Gregory has no fresh injury concerns as he looks for his first win since taking over from Richie Barker earlier this month.