The Arsenal boss had been sweating over the fitness of Mesut Ozil and Olivier Giroud but both have been passed fit for the Group F opener.
Deadline-day signing Ozil had been struggling with tight muscles following his debut against Sunderland while striker Giroud has recovered from the knee knock picked up in the same game.
Centre-back Per Mertescaker is also back in contention after he missed Saturday's trip to the Stadium of Light but Santi Cazorla, Alex Oxlade-Chamberlain and Lukas Podolski are ruled out.
The lack of numbers has seen Wenger turn to his youth system to fill his bench with teenagers Isaac Hayden and Chuba Akpom added to the 18-man travelling party.
Marseille boss Elie Baup welcomes back Ghana winger Andre Ayew to his squad following his one-match suspension.
Ayew was replaced by Florian Thauvin for the 1-1 draw against Toulouse last Saturday and the recent recruit from Lille will now drop to the bench.
You can watch Marseille v Arsenal live on Sky Sports 4HD tonight at 7.30pm.