The final whistle goes and Tottenham have beaten Anzhi Makhachkala 2-0 to take control of Europa League Group K. The Russians battled hard in the second half after earlier goals from Defoe and Chadli, but Spurs never looked like relinquishing their lead.
Chadli picks out Defoe and he tries to skip around the keeper, but by the time he had cut back inside there were bodies back for Anzhi and his attempted pass was easily intercepted.
Tottenham are happy for the clock to tick down as they pass it around with little ambition in midfield.
Lloris is forced into his best save of the night as he dives to his right to parry a well-struck 20-yard volley from Solomatin which bounced awkwardly just in front of him. Luckily the rebound falls to Walker and Spurs are able to get the ball clear quickly.
Yeschenko's volleyed cross from the right wing is headed emphatically clear by Dawson in the middle.
Eriksen doesn't seem to be having any problems with the tricky pitch as he orchestrates a flowing Spurs move which culminates in Defoe smashing a shot high into the stands from just outside the area.
Anzhi have made Tottenham work hard in this second half but have created few genuine opportunities and time is running out now to salvage something.
Anzhi respond with their third and final substitution, with Gadzhibekov replacing Angbwa.
Spurs make their final change as Eriksen comes on for Holtby.
The flag goes up for offside against Defoe following a slick move involving Chadli, Holtby and Dembele.
Dawson needs to be on his toes straight away against the powerful Traore as he makes an important tackle in the area and concedes a corner.
Walker gallops forward from right-back but Anzhi have numbers back in defence and another Spurs move breaks down.
Tottenham make a double change as Dawson and Sigurdsson come on for Kaboul and Lamela. It appears as though Kaboul may be going off as a precautionary measure after picking up a slight knock.
Yeschenko has added some pace to Anzhi's attack but he can find no way through as he darts down the left wing.
It looks for a second as though Solomatin is going to get past Kaboul after a threatening run but the Anzhi player then takes a tumble in the box. It is not clear whether that is a slip or a dive, but there was certainly no contact with the Tottenham player and the referee ignores half-hearted appeals for a penalty.
Anzhi are seeing much more of the ball as Spurs appear content to sit back, but the Londoners still look well organised at the back and will be difficult to break down.
There is a moment of concern for Walker as he goes down clutching his leg after coming off second best in a physical challenge with Traore, but he regains his footing relatively quickly.
Kaboul plays a gentle back-pass to Lloris but the ball takes a slight bobble and the Spurs keeper ends up slicing his kick into touch.
Jucilei blazes a wild effort high and wide from 20 yards as a decent spell of pressure for Anzhi comes to nothing.
Tottenham are certainly being tested now as Ahmedov delivers a teasing cross from the right which is cut out by Kaboul and goes behind for a corner.
Holtby tries his luck with a shot from long range but it lacks the power to bother Pomazan, who makes a comfortable save low down to his left.
A driven cross from Solomatin is parried over his crossbar by Lloris, who then comes out decisively to punch away the corner.
The two Anzhi substitutes link up nicely as Traore shrugs off Sandro before playing in Yeschenko, but his low cross from close to the byline is kicked clear by a diving Lloris.
Anzhi make their second change of the night as Serderov goes off to be replaced by Yeschenko.
The game has been more open since half-time and Anzhi are showing some determination as Solomatin is tackled by Kaboul.
Ahmedov whips in a menacing low cross from the right wing but Lloris is out quickly to intercept with some safe handling.
Lamela drives forward down the right and plays in Chadli, who curls a low shot narrowly wide of Pomazan's left-hand post from 20 yards.
Anzhi commit a few men to attack and Spurs struggle to clear at the edge of their area, allowing Adeleye to fire wide from 25 yards.
Fryers and Chadli combine nicely down the Spurs left and exchange passes to work their way into the Anzhi area before the move ultimately fizzles out.
Serderov shows a burst of pace down the left wing but is not quick enough to escape the attentions of Walker.
Anzhi get the second half started. There has been one change at the break with Traore on for Abdulavov.
The half-time whistle goes and Tottenham are in total control at 2-0 in Russia. It was a tight game for half an hour but goals in quick succession from Defoe and Chadli have put Spurs on course for a second win in Group K. Anzhi have barely threatened and will need to improve significantly after the interval to stand any chance.
Sandro and Dembele provide an excellent shield for Tottenham in the centre of the field whenever Anzhi win possession and it will be a long road back for the Russians.
Tottenham are sensing that they could finish this game off before half-time as they break quickly down the left through Holtby, but the move eventually runs out of steam.
GOAL! Spurs carve open Anzhi's defence all too easily as Chadli makes it 2-0. Walker gets forward well down the right before sending in a low cross which Chadli, unmarked in the centre, calmly guides past Pomazan. It was a low finish which the keeper could perhaps have done better with, but there may have been a slight bobble.
Anzhi win a corner and Lloris is unconvincing as he comes out and flaps at the ball, but the delivery was too heavy anyway and flies harmlessly away to safety.
Anzhi try to respond by raising the tempo but Tottenham quickly regain possession and stay in control with a patient period of passing in midfield.
GOAL! Defoe makes it 1-0 to Spurs from their first real chance of the game. Holtby splits the Anzhi defence with a gem of a pass that puts the England striker through on goal, and he beats the keeper with a powerful finish high into the net from 12 yards.
Holtby takes aim with a curling shot from 25 yards out on the left which is well struck, but Pomazan makes no mistake with a firm punch to safety.
There is a buzz whenever Lamela gets on the ball because it looks like he is capable of doing something special, but so far it has been a frustrating evening for the big-money summer signing.
A lucky break allows Serderov to wriggle free of Sandro in the box but Lloris is again out quickly to smother the ball, and the whistle had gone anyway for a Spurs free-kick.
One of the hallmarks of Lloris' game is how quick he is to rush off his line and clear away any threat, and he is again alert as he beats Solomatin to a loose ball.
Dembele tries to inject a faster tempo into Tottenham's play with a direct run, but Anzhi are camped just outside their own area and there are enough bodies to win the ball.
Anzhi make a rare foray forward but the chance to send in an effective cross is wasted as Tagirbekov's delivery sails harmlessly over Lloris' bar.
Lamela expertly controls a cross on his chest and spins nicely, but then gives away possession with a wayward pass.
Holtby is well tackled by Adeleye to break up a promising Tottenham move emanating down the left.
Tottenham remain largely patient in their build-up play before Chadli attempts a killer ball through the middle and sees his ambitious pass intercepted.
Lamela links up well with Sandro but then loses control of the ball and is dispossessed by Tagirbekov.
There have been a few stumbles and slips on a surface which does not look the best, and perhaps as a result Tottenham's passing has not been up to their usual standard.
Tottenham are bossing possession at the moment but there is not a lot of urgency and Anzhi look relatively untroubled at the back.
Sandro tries his luck with a shot from distance which bobbles along the turf and forces Pomazan to keep a close eye on the ball as he dives low to his left.
There is a strange atmosphere at the ground, which is just outside of Moscow and 1,000 from home for Anzhi as they are not allowed to play in troubled Dagestan. There is plenty of support for Anzhi but some of the locals are also behind Tottenham.
Sandro's no-nonsense clearance relieves the pressure for Tottenham following a long free-kick from Anzhi.
The Russians may have targeted Chiriches as a possible weak link as Solomatin tries to beat the Spurs defender but is held up by a well-timed challenge in the area.
Anzhi's approach appears quite direct and they will probably have to find a bit more subtlety if they are to break down a Spurs defence which has been solid all season.
Serderov tries to use his pace down the left wing for Anzhi but Walker is easily up to the challenge and stays strong to see the ball out of play.
Spurs are nearly caught napping at the back as Solomatin races on to a long ball through the middle, but as Lloris rushes out to try and avert the danger it becomes apparent that the flag has been raised for offside.
Lamela looks eager to impress as he gets on the ball and drifts inside his defender, but then plays a loose pass to surrender possession.
Spurs enjoy a period of early possession in midfield as the game sets off at a gentle tempo. It is a chilly night in Russia and many of the players are wearing gloves.
Tottenham kick us off in Russia and let us hope for an exciting encounter in this Europa League group game.
Anzhi Makhachkala: Pomazan, Angbwa, Tagirbekov, Adeleye, Ewerton, Jucilei, Ahmedov, Razak, Solomatin, Serderov, Abdulavov. Subs: Kerzhakov, Yeschenko, Gadzhibekov, Grigalava, Gatagov, Demidov, Traore.
A long trip to Russia is never ideal for an English team and Anzhi have been an emerging force in European football over the past few years, but this season they are struggling towards the bottom of their domestic league. They encountered financial problems during the summer and had to sell a host of top players, including Samuel Eto'o, Willian and Christopher Samba. Guus Hiddink left as manager in July and his replacement, Rene Meulensteen, last just 16 days before being sacked. Gadzhi Gadzhiev is the new man at the helm but does not have the same sort of talent at his disposal as the club once did.
Villas-Boas will feel that he has a good enough squad to challenge on multiple fronts this season and this evening's match is another opportunity for some players to show they should be starting more regularly. The likes of Erik Lamela, Nacer Chadli and Vlad Chiriches have not established themselves as quickly as other summer signings such as Christian Eriksen and Paulinho, but have their chance to shine today. Jermain Defoe and Lewis Holtby are also included and have impressed when they have been called upon this term.
Tottenham had to settle for a 1-1 draw against London rivals Chelsea at the weekend in a match somewhat overshadowed by Fernando Torres' sending-off and a row between the two managers about Jan Vertonghen's involvement in the Spaniard's dismissal. It was another solid performance from Spurs, though, who are currently third in the Premier League and have got off to winning starts in the Capital One Cup and Europa League.
Tottenham: Lloris, Walker, Chiriches, Kaboul, Fryers, Dembele, Sandro, Lamela, Holtby, Chadli, Defoe. Subs: Friedel, Dawson, Naughton, Eriksen, Sigurdsson, Kane, Soldado.
Get in touch with your views and predictions at Lewis.Rutledge@bskyb.com, or via Twitter @SkySportsLewis. Can Tottenham continue their strong start to the season or will they come unstuck in Russia? Andre Villas-Boas has rung the changes so which players are you most excited about following this evening?
Welcome to our minute-by-minute commentary of Tottenham's Europa League clash against Anzhi Makhachkala. It is the second game for both sides in Group K, after Spurs cruised to a 3-0 home with over Tromso last month and Anzhi played out a 1-1 draw with Moldovan side Sheriff Tiraspol.