Tom Eaves is available for Shrewsbury's home clash against League One promotion chasers Leyton Orient but fellow loanees Adam Reach and Cameron Gayle have departed the club.
All three players featured in Town's 2-1 victory at Oldham on New Year's Day, the last of their loan agreements at the Shropshire oufit.
Bolton striker Eaves has since extended his stay until the end of the season but forward Reach and defender Gayle have returned to parent clubs Middlesbrough and West Brom respectively.
Gozie Ugwu, who did not make the matchday 18 against Oldham, has also gone back to Reading, while defender Jermaine Grandison is closing in on his return to full fitness.
Kevin Lisbie is set to return to the Leyton Orient side for the trip to Shrewsbury.
The 12-goal striker was rested for Saturday's 4-0 FA Cup defeat at Yeovil and could be joined in attack by Tottenham loanee Shaquile Coulthirst, who made his O's debut as a sub at Huish Park.
But boss Russell Slade has a host of injury concerns as he bids to leapfrog Wolves back into the top two.
Romain Vincelot is set to miss out again with a knee injury, Robbie Simpson has a hamstring problem and Jamie Jones (back), Shaun Batt (hamstring) and David Mooney (foot) are still on the sidelines.