Stuart McCall's side brought in Twardzik on emergency loan last month due to injuries to both Hollis and Gunnar Nielsen.
While Nielsen is fit again and should start in Saturday's SPL clash against Hearts, Hollis is continuing to struggle with his ankle.
If Hollis fails to recover, Motherwell assistant boss Kenny Black admits the club might go back in for Twardzik, who helped Well to win five games on the bounce to climb into the top three in the SPL before he returned to Dens Park last week.
Black told the Daily Record: "Dan did well for us but Gunnar is available again, which is a boost. We've also had a few problems with Lee and his ankle.
"If he doesn't recover, we might have to consider bringing Dan in again, depending on his situation at Dundee, or look elsewhere.
"We'll see how it goes between now and the weekend."
He added: "He seems to have a few good days and then he suffers a little bit of a reaction.
"We've given the players a few days off and we'll assess things as the week progresses."