The Senegal striker has failed to score in the Premier League since the Toon's 1-0 victory over Fulham on April 7, with his only goal this season coming in the Capital One Cup win over Leeds in September.
Despite a poor run of form, the Magpies boss has praised Cisse's attitude in training and is confident he will become one of the league's most-feared strikers again.
"He's a big player for us and we need him in the goals. I've been really boosted by his personality and performance," he told the Daily Express.
"Papiss has been doing exceptionally well in training and his attitude has been first class. Like any striker, he wants to be in there scoring goals, taking chances and getting on the end of things.
"I'm sure that will happen," he added.
"He has been brilliant, our best player on the training ground and that's good to see."
Ahead of the Saturday Night Football match with West Bromwich Albion, midfielder Moussa Sissoko believes Newcastle can continue their impressive form, after three successive wins left the Magpies just two points off the Champions League places.
He told the Daily Star: "If we work hard every week, I think when the season finishes we could be in the top seven or eight."