Garde was quizzed about France attacking midfielder Grenier after it emerged that Paris Saint-Germain had struck a deal with Newcastle for Cabaye.
Newcastle already had Cabaye's international colleague on their radar, and it is understood they could now test Lyon's resolve for the 23-year-old.
But Garde believes that, like they did when Napoli came in for Maxime Gonalons, they will stand firm.
"The Clement case, I have not discussed with my president. You tell me the interest of Newcastle," he told RMC.
"For Clement, I think it will be the same as with Max [Gonalons]."
Grenier also spoke about the interest from Newcastle and revealed that Lyon president Jean-Michel Aulas had earlier told him that he might consider an offer.
When asked about Newcastle, Grenier said: "I have only just learned about [Newcastle's] interest from the press, like you.
"I have no idea what can be said or done at this time. At one point, the president said that if a good offer is made for me this winter, he would look at it.
"I do not know if he received an offer or not and I'm not at all thinking about it.
"For the moment, it is not in my head. I have goals with Olympique Lyonnais for the end of the season, in the short term. I focus on it.
"The World Cup is one of my goals. It is in a small corner of my mind. Is it better for me to stay in Lyon? For the moment, yes. There are still many goals for me with Lyon."