The midfielder, who grew up in the Turin club's youth system, has been mooted as a target for the Premier League club in recent weeks.
However, when pressed by the Italian media on Friday, the Italian international made it clear that his future is black and white.
Marchisio said: "I don't see myself far away from Juventus. It would be absurd to leave now that we have started winning.
"I'm not interested in the rumours, I'm happy at Juventus and I want to renew my contract."
The idea behind the proposed Marchisio sale, who is tied to the Old Lady until 2016, is that it would raise funds to possibly re-sign Paris Saint-Germain's Zlatan Ibrahimovic.
Marchisio added: "Ibra is a player who has always won in all the jerseys that he has worn. If he arrives then we would welcome him with open arms.
"All players who can help us to grow would be accepted. These are situations for the club to consider, but he is certainly a great player."