Competition for attacking places at Old Trafford is so fierce that Macheda has found himself a long way down the pecking order this season, with the likes of Robin van Persie, Wayne Rooney, Javier Hernandez and Danny Welbeck blocking his route to the first team.
He has been loaned out to Sampdoria and Queens Park Rangers at the halfway point of the previous two seasons, and agent Giovanni Bia admits he will probably move on once again this January.
Bia told tuttomercatoweb.com: "Federico at this time is not finding space, and so it is clear that in January he will go away.
"But I don't think he'll be back again in Italy because usually in January clubs are looking for players that are already ready, unless there are teams with a quiet standing which want to do long-term projects with him."
Macheda has been at Manchester United since making the move to England as a 16-year-old in 2007.